Tissue engineering encompasses aspects of cells, materials, and biochemical, and physiochemical cues to restore, maintain, or replace tissue function. Disease modeling, whether it be in vitro or in vivo, aims to establish systems that resemble human diseases to improve our understanding of the mechanism of diseases or develop new therapies and diagnostic tools. Though these two areas are distinctly different in their end goals, there is significant conceptual and design overlap. Presentations in this session focus all aspects of tissue engineering or disease modeling including biomaterials, cells, growth factors, mechanical stimuli, and in vivo models and testing.