TECHNOLOGY SUMMARY
3D NGMS-Seq is a new tool that reads RNA molecules directly and accurately, even when they're mixed or modified. Unlike older methods, it doesn’t need a reference sequence. It uses advanced mass measurements and smart algorithms to uncover hidden RNA variants, helping improve RNA-based drug development and quality control.
AREA/MATURITY/AWARDS
Primary Application Area: Biotech & Medical
Technology Development Status: Ready to Market
Technology Readiness Level: TRL 9
Vetted Programs/Awards: 1. 1R41HG013624-01 (NHGRI) Title: High-throughput direct sequencing and quantitative mapping of RNA modifications using mass spectrometry Award: $406,500; 09/18/24-08/31/26 2. 1R41HG014125-01 (NHGRI) Title: Exhaustive de novo RNA sequencing of every RNA in a sample by a layer-by-layer mass spectrometry ladder intensity approach Award: $215,088; 09/25/24-08/31/26
MARKET KEYWORDS
Market Keywords: academic/research market, an RNA therapeutics market, and RNA drug compliance