NSF I‑Corps Spin‑Out: HYDROGENISE - Hydrogen Generation through Integrated Sustainable Electrolysis for Scalable Clean Energy

S. Bashir, P. Robinson, J.L. Liu
Texas A&M University-Kingsville,
United States

Keywords: hydrogen production, electrolysis (PEMEC), nanostructured catalysts, clean energy commercialization, university spin‑out innovation

Summary:

The program Hydrogen Generation through Integrated Sustainable Electrolysis (HYDROGENISE) represents a university‑driven innovation with the potential to transform hydrogen production and catalyze regional economic growth. Originating from Texas A&M University-Kingsville (TAMUK), the HYDROGENISE team brings together a multidisciplinary group of scientists and entrepreneurs: Dr. J. Louise Liu, Technical Lead; Dr. S. Bashir, Entrepreneurial Lead; and Dr. P. Robinson, Industry Mentor. Professors Liu and Bashir co‑founded Louise Nanoinnovation North America (LNNA) to transition nanostructured energy materials from laboratory research to commercialization, while mentoring students and building inclusive pathways for the next generation of innovators. At its core, HYDROGENISE advances decentralized hydrogen production through proton exchange membrane (PEM) electrolysis cells. Current commercial electrolyzers operate at ~50 kWh per kilogram of hydrogen, producing 200 kg per hour at the 10 MW scale. HYDROGENISE improves upon this baseline by employing proprietary non‑precious group metal/metal oxide catalysts that enable water splitting without costly pretreatment. The system achieves Faradaic efficiencies of 90–100%, with 50% higher water‑splitting rates compared to commercial catalysts, while reducing overpotential. In prototype testing, the technology improved hydrogen fuel cell vehicle mileage by 45% and extended drive time by 52%. These advances demonstrate both technical merit and market‑ready differentiation. The project’s intellectual merit lies in its integration of nanomaterials science, electrochemistry, and systems engineering into a reproducible, scalable platform. By leveraging green chemistry methods such as sol‑gel synthesis, solid‑state reactions, and chemical vapor deposition, the team ensures stoichiometric control and reproducibility. In situ analytics and SPC-gates provide traceability and audit‑ready workflows aligned with CHIPS Act requirements. This rigorous approach positions HYDROGENISE as a scientific breakthrough and credible candidate for industrial adoption. The broader impacts extend well beyond the laboratory. HYDROGENISE addresses three pressing societal challenges: environmental sustainability, energy independence, and economic development. Environmentally, the system reduces greenhouse gas emissions by up to 30% compared to conventional hydrogen production. From an energy perspective, it decreases reliance on fossil fuels by enabling distributed, renewable‑powered hydrogen generation. Economically, the initiative stimulates growth in South Texas by creating jobs, developing a skilled workforce, and establishing a domestic supply chain for clean energy technologies. The team projects cost savings of 35% ($2.6–3.9 per kilogram of hydrogen) and a 50% boost in energy efficiency by 2028, with the goal of capturing 0.001% of the $170 billion global hydrogen market. The commercialization pathway is equally compelling. Customer discovery interviews have identified demand across ammonia production, sustainable aviation fuels, and hydrogen fuel cell vehicles. HYDROGENISE’s three‑step strategy (Sea Hydrogen Landing, Green Production, and the Four‑Station Joint Model) leverages coastal Texas wind and seawater resources to integrate hydrogen with oil, gas, and electricity infrastructure. Partnerships with the Defense’s APEX Accelerator and potential collaborations with Air Liquide and other industry leaders further strengthen the market trajectory. In sum, HYDROGENISE exemplifies how university spin‑outs can drive economic impact by translating cutting‑edge research into scalable, market‑ready solutions. By combining technical innovation, entrepreneurial leadership, and community engagement, the team is building a resilient clean energy enterprise that advances U.S. competitiveness while addressing global sustainability challenges.