Department of Energy Biomanufacturing Product and Tool Development for Industry Adoption

J. Colangelo
National Renewable Energy Laboratory,
United States

Keywords: SAF, alkane, ethanol, muconic acid, hydroxypropionic acid, DOE


The Agile BioFoundry (ABF) is a consortium of Department of Energy (DOE) National Laboratories conducting research and development to accelerate domestic industrial biomanufacturing. The ABF is currently working on two pathways for biofuels alongside two pathways for biochemicals production. This talk will focus on recent developments in increasing the efficiency of production of 1) sustainable aviation fuel blend components ethanol and alkane-rich molecules, 2) muconic acid, a precursor for numerous industrial chemicals (e.g., adipic acid, terephthalic acid) and performance-advantaged bioproducts, and 3) 3-hydroxypropionic acid, a precursor for acrylic acid, acrylonitrile, methylacrylate, and others. Current process models, techno-economic analyses (TEA), life cycle assessments (LCA), and development priorities associated with these processes will be presented. Additionally, ABF tools and capabilities are available to industry partners for collaborative work, and the technical capabilities of the ABF will be described. These tools include innovations in host onboarding, and pathway, strain, and process design, including LCA and TEA. Finally, a brief overview of mechanisms by which to partner with the ABF to leverage its capabilities for industrial applications will be discussed.