Safety concerns of foodborne Inorganic Nanoparticles: titanium dioxide nanoparticles adversely impact gut microbiota

Hang Xiao

Associate Professor

University of Massachusetts Amherst

Epidemiological evidence has indicated that diet abundant in fruits and vegetables may reduce the risk of chronic diseases such as cancer, and this effect has been attributed to bioactive components present in these foods. For example, it was estimated that one third of cancer cases might be preventable by dietary modification.

My research is focused on identifying potential disease preventive dietary components (nutraceuticals), elucidating their molecular mechanisms, investigating possible synergistic interactions among these dietary components and commonly used pharmacological compounds, enhancing biological activities of dietary components by food processing and nanotechnology, with the long-term goal of developing diet-based strategies for the prevention of chronic diseases. The major approach of this research is the utilization of chemical, biochemical & molecular biology in cell cultures combined with in vivo animal models for human diseases.