Nanoparticle Design for Commercial Photothermal Therapies

M. Miranda, A. Saunders, S. Oldenburg
nanoComposix,
United States

Keywords: nanoparticles, nanomedicine, photothermal, plasmonics, therapy, device

Summary:

Photothermal therapies leverage the optical properties and biocompatibility of various types of nanoparticles for effective and safe treatments for a wide variety of conditions and diseases. One class of nanoparticles used for biomedical photothermal applications are plasmonic nanoparticles made from various sizes and shapes of gold and silver that efficiently convert light to heat. Selecting the optimal particle size and geometry for a target application is a multi-factor decision that requires the evaluation of the particle’s peak wavelength, the particle size, the absorbance and scattering cross sections, the surface chemistry, and the stability of the particle in relevant biological media.