ANPs strongly scatter light, such that quantification is then a simple matter of particle counting and can be automated through image analysis software. Furthermore, it is possible to control the color of the ANPs by controlling their composition. Thus, ANPs with different colors can target different markers simultaneously for multiplexed detection. ANPs offer a stable signal because they do not suffer from photobleaching. Moreover, the strong optical allows direct immunolabeling without the need for secondary antibodies such that the preparation time is significantly reduced and multiplexing should be free from cross-reactivity. The target application is immunolabeling of biopsy tissues for cancer diagnosis and personalized treatment selection. Different markers (proliferation markers, hormone markers...) have already been identified in correlation with specific treatments for number of high incidence cancers such as breast cancer and lung cancer.
Primary Application Area: Medical Devices
Technology Development Status: Prototype
Technology Readiness Level: TRL 4
Organization Type: Academic/Gov Lab
Showcase Booth #: 313
GOVT/EXTERNAL FUNDING SOURCES