Texas Tech University, Lubbock, TX, US
Nematodes, especially C. elegans, have proven to be an effective model organism to investigate aging biology, neurodegenerative disorders, and age-related diseases. However, manual analysis of experiments related to the health and lifespan of nematodes can be highly labor-intensive, limiting experimental throughput. This new microfluidic device offers a method to remove progeny while efficiently retaining the adult worms in the device. The multi-purpose device can be used to measure lifespan curves, record health span measures, conduct drug and RNAi assays, and quantify muscle strength as a function of age. The device also provides the ability to add or remove reagents at any point, enabling novel cross-sectional and longitudinal aging experiments.
Primary Application Area: Biotech, Pharma, Medical Devices
Technology Development Status: Prototype
Technology Readiness Level: TRL 3
Organization Type: Academic/Gov Lab
Showcase Booth #: 530
GOVT/EXTERNAL FUNDING SOURCES