Reusable Biosensor for Detecting Diabetes by Microwave LC Resonator on Integrated Passive Design (IPD) Process

E.S. Kim, Z. Chuluunbaatar, C. Wang, Z. Yao, K.K. Adhikari, N.Y. Kim
Kwangwoon University,

Keywords: IPD, biosensor, RF


This works present a level-free biosensor for detecting diabetes with high sensitivity and rapidity by microwave LC resonator based on integrated passive device (IPD) technology. The structure of the proposed consists of the square meandered line coupling capacitor in the air bridged circular spiral inductor on a gallium arsenide (GaAs) substrate. This developed biosensor resulted in a good dynamic performance for the deionised water glucose concentration from 50 mg dl-1 to 250 mg dl-1. Detection method of diabetes is performed by inserting blood-glucose concentration in human blood. The blood-glucose concentration level is determine by amount of frequency shift to the lower region indicated in coupling capacitor between the two halves of a circular spiral inductor that exhibit self-resonating impedance. The resonant frequency of the biosensor resonator is fixed to 1.627 GHz and is suitable for sensing glucose concentration measurement. For the simulation analysis, we considered the variation of dielectric constant of the blood, as the level of the glucose varies, and it is reflected by the frequency shift by the return loss (S21) response of the resonator. The biosensor can be reused and can be applied for the real time detection of glucose level in the serum of diabetes patients during the point of care testing.