Novel fluorescent nanoparticles for ultrasensitive identification of nucleic acids by optical methods

M. Westergaard Mulberg, M. Taskova, A. Okholm, J. Kjems, K. Astakhova
University of Southern Denmark,

Keywords: fluorescent nanoparticles, optical methods, nucleic acid identification, amplication-free methods


There have been an enormous interest in new amplification-free detection methods. A tremendous progress has been made in fluorescence based optical detection of biomolecules, which here resulted in the synthesis of novel ultra bright fluorescent nanoparticles attachable to target-specific DNA probes.