E. Lopez-Bernardo, E. Irvine, R. Ulijn, D. Lightbody
Keywords: biomaterials, model tissues, 3D printing, bioprinting, cell culture, functional materials, biomimetic materials
Summary:Biogelx Limited is a biomaterials company that designs tuneable peptide hydrogels, offering artificial tissue environments to cell biologists for a range of cell culture applications. The hydrogels are highly tunable, cell-matched biomaterials, capable of revolutionizing the way cell biologists control and manipulate cell behavior in the laboratory. This is of direct relevance to fundamental cell research, including the study of stem cells and disease models within academic and medical labs. However, the major commercial significance this has is the dramatic impact on the development of cell-based assays and drug discovery/toxicology platforms within large pharmaceutical companies. Biogelx offers a range of hydrogel platforms that are three dimensional (3D), 99% water and have the same nanoscale matrix structure as human tissue. This gives control back to the cell biologist, as the gels can be tuned to meet the needs of any given cell type. This poster showcases the underlying chemistry of Biogelx’s peptide hydrogels, highlighting the range of chemical and mechanical modifications that can be implemented within the gels, in order to address a wide range of cell based applications. Some examples of academic and industrial collaborative work are also presented, include how the gel tunable properties, can be use to influence the differentiation pathway of stem cells.