Statistical Modeling of Fluoride Release Profiles of Various Dental Restorative Materials in Three Buffer Solutions

A.B.H. Yoruç, İ. Batmaz
Yıldız Technical University,

Keywords: fluoride release, fluoride ion specific electrode, dental restorative materials, organic acid buffer solutions, fluoride release profiles, statistically modeling


This study compare the fluoride release profiles of two glass ionomer cements (GICs) and three resin-modified glass ionomer cements (RMGICs) by using statistical modeling. Commercial disc specimens were prepared using a cylindrical teflon mold and placed into organic acid buffer solutions (AAB: Acetic Acid Buffer; CAB:Citric Acid Buffer and LAB: Lactic Acid Buffer) with a costant pH value of 4.1. Fluoride release was measured using a fluoride-ion spesific electrode at different time intervals up to 168 hours. Then, data obtained non-cumulatively were statistically analyzed, and the fluoride released profiles were compared. The highest fluoride release was obtained from the RMGIC (PhotacFil Quick) in AAB, CAB and LAB solutions. This was followed by RMGIC (Vitremer) and GICs (Ketac Cem, Fuji Plus and Aqua Cem) in all solutions, respectively. Fluoride release profiles of materials KTC, FP and AC (Group 1) have completely different characteristics to that of the materials PFQ and V (Group 2). Therefore, two separate linear regression model development studies are attempted to for Group 1 and Group 2 materials. Fluoride release patterns of Group 2 materials (PFQ and V) do not all have similar characteristic at all solutions. To illustrate, the fluoride release profile of PFQ in AAB and LAB, and that of V in AAB and LAB are similar, and can be modeled by using even simple linear regression. Although there are some similarities, fluoride release profiles of Group 1 materials in different solutions are significantly different from each other. The development of statistical models for fluoride release can be supportive alternatives to compare the fluoride release behavior of dental materials and also be helpful in understanding and eliminating the factors which are responsible for the formation of fluoride release amounts for the production of new generation materials.