Biosensing, Diagnostics & Imaging

Symposium Co-Chairs

Srinivas IyerSrinivas Iyer
Bioscience Division
Los Alamos National Laboratory

Confirmed Invited Speakers

William C. Florence
Medical S&T Division, Vaccines Chemical and Biological Technologies
John WikswoJohn Wikswo
Gordon A. Cain University Professor
Vanderbilt University
Marc Luebberstedt
Charité - Universitätsmedizin Berlin, Germany
Kevin Kevin "Kit" Parker
Tarr Family Professor of Bioengineering and Applied Physics
Harvard University
Kapil Pant
Director of Biomedical Technology
CFD Research Corporation

Symposium Sessions

Monday May 13

2:00INTO-RAM ATHENA: Multi-organ Platform for Rapid Assessment of Medical Countermeasures - DTRA Special Session
Biosensing, Diagnostics & Imaging I - Posters 4:00

Tuesday May 14

10:30Innovation Spotlights: Biotech & Biosciences
11:00Biosensors: Nanoparticles in Imaging Technologies
Biosensing, Diagnostics & Imaging II - Posters 1:30
3:00Biosensors: Clinical/health Applications
4:30Innovation Spotlights: Pharma & Medical Devices

Wednesday May 15

8:30Biosensors: Novel Approaches & Instrumentation
11:00Innovation Spotlights: Pharma & Biotech
4:00Innovation Spotlights: Medical Devices

Symposium Program

Monday May 13

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2:00INTO-RAM ATHENA: Multi-organ Platform for Rapid Assessment of Medical Countermeasures - DTRA Special SessionAzalea 2
Session chair: William C. Florence, DTRA - JSTO & Rashi Iyer, Defense Systems & Analysis, Los Alamos National Laboratory, US
2:00Engineering In Vitro Human Organ Platforms (invited presentation)
J. Wikswo, Vanderbilt University, US (bio)
2:50SYN-TOX: A Microfluidic Co-culture Platform for Drug Toxicity Assays (invited presentation)
K. Pant, CFDRC, US (bio)
3:15Use of Hollow Fibers in 3D-Liver Cultures (invited presentation)
M. Luebberstedt, Charité - Universitätsmedizin Berlin, DE (bio)
3:40In vitro Lung Organ Development for Rapid and High-throughput Bioassessment (invited presentation)
R. Iyer, Los Alamos National Laboratory, US
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Biosensing, Diagnostics & Imaging I - Posters 4:00Expo Hall A
-Synthesis and Characterization of Functionalized Magnetic Nanoparticles for Biomedical Applications
L.F. Wang, Y.L. Lo, J.H. Ke, Kaohsiung Medical University, TW
-Composite nano carriers for multimodal imaging and drug delivery by a versatile block copolymer assembly process
R.K. Prud’homme, Princeton University, US
-A Novel Near Infra-Red Fluorescent Probes to Repair Metal Artifact After Implantation
L-H Chiu, F-C Kung, M-C Yang, Y-H Tsai, W.H. Chang, W.-F.T. Lai, Taipei Medical University, Harvard Medical School/McLean Hospital, TW
-Direct Spatiotemporal Visualization of Tyrosine Phosphorylation Dynamics in Live Cells by Biocompatible Aggregation-Induced Emission Peptide
X. Zhang, Y. Zhao, G. Zou, X-J Liang, National Center for Nanoscience and Technology, CN
-Methods of colloid vibration imaging for characterisation of nano-particle suspensions
M. Wang, M. Hosseini, L. Bramson, J.I. Khan, University of Leeds, UK
-Imaging the Distribution of High Colloidal Stability Mesoporous Silica Nanoparticles (MSNs) with PET and MRI
M. Laprise-Pelletier, J.-L. Bridot, R. Guillet-Nicolas, J. Lagueux, Y. Gossuin, S. Laurent, L. Vander Elst, F. Kleitz, M.-A. Fortin, Université Laval, CA
-Luminescent Water Soluble Carbon Quantum Dots for Bio-imaging and Target Drug Delivery
A. Allam, A. Allam, Cromoz Inc, US
-Novel nanotechnology to concentrate and preserve Trypanosoma cruzi antigens in urine of Chagas disease patients co-infected with HIV virus
Y.E. Castro-Sesquen, R.H. Gilman, M. Reimer, C. Mejia, E. Valencia, L. Liotta, C. Bern and A. Luchini, George Mason University, US
-AFM resolves dynamic effects of ethambutol on nanomechanics and nanostructures of single dividing mycobacterium cells
Y. Wu, R.C. Sims, A. Zhou, Utah State University, US
-Ultra-High Performance Immunosensor Prepared by Glassy Carbon Electrode Modified with Nano Gold Particles and Antibody
D. Assan, M. Mozneb, J.C.K. Lai, S.W. Leung, Idaho State University, US
-Aerosol manufacturing of plasmonic biosensors with silica coated nanosilver
G.A. Sotiriou, C.O. Blattmann, S.E. Pratsinis, ETH Zurich, CH
-Performance Comparison of Immunosensors Modified with Polymers, Nanoparticles and Antibody
S.W. Leung, J.C.K. Lai, D. Assan, Idaho State University, US
-Development of a high sensitivity fluorescence immunoassay for Amyloid Beta 42 by a silicon microarray platform
M. Cretich, P. Gagni, L. Sola, M. Chiari, Consiglio Nazionale delle Ricerche, IT
-Disposable Electrochemical Immunosensor for Cancer Biomarker Detection
R. Laocharoensuk, P. Duangkaew, N. Apiwat, S. Tapaneeyakorn, T. Dharakul, National Science and Technology Development Agency, TH
-Highly Sensitive Biosensor for Monitoring Colorectal Cancer Biomarkers
A. Malima, Biolom LLC, US
-SERS Analysis of Dopamine Using Chitosan-gold Nanoshell on Optical Fiber
J-W Lim, I-J Kang, Gachon University, KR

Tuesday May 14

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10:30Innovation Spotlights: Biotech & BiosciencesPotomac 2
Session chair: Adi Treasurywala, ArrowCan Partners Inc., Reviewer Panel: Allen Dines, University of Wisconsin-Madison, Lily Khidr, Elsevier
10:30iTester Hand-Held Multi-Assay Reader
T. Vail, Northern Arizona University, US
10:37Fixative of Polymerized Carbon Nanotubes Encapsulating Osmium Nanoparticles for Biological Tissue
N. Sarlak, University of North Carolina in Chapel Hill, US
10:44III-V Nitride Microcantilever based Photocoustic Biosensor
J. Propst, University of South Carolina, US
10:51Membrane-based technology for bioprocessing
S. Ivanov, Macro Biosystems, Inc., US
10:58Luminescent Water Soluble Carbon Quantum Dots for Bio-imaging and Target Drug Delivery
A. Allam, Cromoz Inc, US
11:05Cerebrolysin for treatment of neuropathic pain
H. Sharma, Uppsala University, SE
11:12Fibronectin Matrix Mimetics
P. Emmerling, University of Rochester, Office of Technology Transfer, US
11:19Improved Cellulose Hydrolysis Activity
E. Payne, National Renewable Energy Laboratory (NREL), US
11:26Highly sensitive Raman-based multiplexing drug screening system
Y.D. Suh, Korea Research Institute of Chemical Technology(KRICT), US
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11:00Biosensors: Nanoparticles in Imaging TechnologiesAnnapolis 1-2
Session chair: Srinivas Iyer, Bioscience Division, Los Alamos National Laboratory, US
11:00Nanoparticles-based Dual-Modal Ultrasound Contrast Agents
W.H. Chang, C.-A.J. Lin, F-C Kung, J-L Shen, W-H Chan, C-K Yeh, W.-F.T. Lai, Chung Yuan Christian University, TW
11:20Dynamic Multispectral Optoacoustic Tomography (MSOT) Imaging as a Novel Tool for Whole-Body Investigation of Nanoparticle Biodistribution and Tumor Perfusion
W.H.P. Driessen, N.C. Burton, J. Claussen, S. Morscher, T. Sardella, D. Razansky, V. Ntziachristos, iThera Medical, DE
11:40A Nanodiamond is Forever: Functionalizable fluorescent nanodiamonds that do not photobleach or blink for in vitro and in vivo imaging
A. Bumb, S. Sarkar, M. Brechbiel, K. Neuman, National Heart, Lung, & Blood Institute, US
12:00Development and Application of a Rod and Sphere-Shaped Viral Nanoparticle MRI Contrast Agent for Atherosclerosis Diagnosis
M.A. Bruckman, N.F. Steinmetz, Case Western Reserve University, US
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Biosensing, Diagnostics & Imaging II - Posters 1:30Expo Hall A
-The scavenging of reactive oxygen species and the potential for cell protection by fullerenols with different isoelectric points
J. Li, R. He, Y. Chang, M. Zhang, X. Liu, J. Jin, B. Sun, Y. Zhao, G. Xing, Chinese Academy of Sciences, CN
-Magnetization of hydrogel particles: a novel urine tuberculosis antigen test
L. Paris, A. Cox, E. Petricoin, L. Liotta, A. Luchini, George Mason University, US
-Nanofabrication Techniques for Fully Integrated Sensing Platforms
M. Mujeeb-U-Rahman, D. Adalian, M. Sencan, A. Scherer, California Institute of Technology, US
-Microfilter with 3D nanotopography for efficient isolation and culture of circulating tumor cells
O.V. Makarova, R. Divan, P. Zhu, D. Adams, S. Li, P. Amstutz, C.-M. Tang, Creatv MicroTech Inc., US
-Novel sensing device based on potentiometric measurement for the detection of lithium
S. Merzouk, N. Zine, M. Tahajanan, M. Agouzoul, J. Bausells, F. Teixidor, N. Jaffrezic-Renault, A. Errachid, Institut des Sciences Analytiques, FR
-HDCR: A novel method for the diagnostic detection of methylated DNA for blood based cancer diagnostics
P. Molloy, K. Rand, T. Ho, C. Lindall, CSIRO, AU
-Development of Novel Nanomaterials for Sampling and Improved Assay of Analytes of Interest to National Security
M.G. Warner, M.J.O. Hara, C.L. Warner, J.C. Carter, W. Chouyyok, J.A. Maclellan, R.S. Addleman, Pacific Northwest National Laboratory, US
-Integrated Nano-Structured Sensor System for Category B Toxins Detection in Complex Biological and Environmental Matrices
P. Takhistov, CH. Chai, Rutgers, the State University of New Jersey, US
-Photoelectrochemical Sensor Based on CdSe/ZnS Quantum Dots and Sarcosine Oxidase
M. Riedel, G. Goebel, F. Lisdat, Technical University of Applied Sciences Wildau, DE
-Probing the Distribution of Gliadin in Dough and Baked Bread Using Conjugated Quantum Dots as a Labeling Tool
S. Ansari, J. Kokini, University of Illinois at Urbana-Champaign, US
-Nanoparticle replica filters
C. Zafiu, D. Willbold, E.-K. Sinner, University of Natural Resources and Life Sciences, Vienna, AT
-Challenges in the Characterisation of Therapeutic Protein Formulations
S. Ball, M. Pothecary, P. Clarke, C. Murphy, Malvern Instruments, UK
-Rapid Evaluation of Bacterial Antibiotic Resistance
G. Longo, L. Alonso-Sarduy, J. Pekkanen, G. Dietler, S. Kasas, Ecole Polytechnique Federale Lausanne, CH
-Study the Correlations Between Direct Electron Transfer Rate Constants in Four Types of Nanobiomimetic Sensors and the Ability to Kill Cancer Cells from Anti-Cancer Candidate Compounds
E.T. Chen, J. Thornton, C. Ngatchou, S-H. Duh, P.T. Kissinger, Advanced Biomimetic Sensors, Inc., US
-From Viruses to Cells: Tuneable Resistive Pulse Sensors for High Resolution Characterization of Nano to Micro-Scale Particle Solutions
D. Kozak, W. Anderson, R. Vogel, M.F. Broom, Izon Science, US
-Towards Wireless Implantable Pressure Sensor to Monitor Compartment Syndrome in Trauma Victims
Y. Wang, C. Allen, S. AL-Qahtani, A. Merdassi, V.P. Chodavarapu, E. Harvey, J. Henderson, McGill Universiy, CA
-Dual-aptamer-based delivery vehicle of doxorubicin to both PSMA (+) and PSMA (–) prostate cancers
H. Jo, C. Ban, Pohang university of Science and Technology, KR
-In vitro biosensing based on magnetically induced motion of magnetic nanoparticles
A. Dangl, G. Kokkinis, F. Keplinger, I. Giouroudi, Vienna University of Technology, AT
-Visual quantification of melamine using citrate-capped gold nanoparticles
N. Li, University of Miami, US
-Detection of novel endocrine-disrupting chemicals in the water
D.A. Stavreva, L. Varticovski, G.L. Hager, National Cancer Institute, US
-Real-Time Electronic Detection of Water/Food Borne Pathogens
M. Potter, BiSen Tech LLC, US
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3:00Biosensors: Clinical/health ApplicationsAnnapolis 1-2
Session chair: Srinivas Iyer, Bioscience Division, Los Alamos National Laboratory, US
3:00Plasmonic nanodome array fabricated on plastic as a dual-mode surface plasmon resonance and surface-enhanced Raman scattering sensor
C.J. Choi, S. Semancik, National Institute of Standards and Technology, US
3:20Amplified On-Chip Fluorescent and Colorimetric Detection of DNA and RNA Hybridization by Surface-Initiated Enzymatic Polymerization
V. Tjong, H. Yu, A. Hucknall, A. Chilkoti, Duke University, US
3:40Gold Nanoparticle Chemiresistors as a Generic Platform for Sensing
E. Chow, B. Raguse, L. Wieczorek, J.S. Cooper, L.J. Hubble, M.S. Webster, K.-H. Müller, CSIRO, AU
4:00Polymeric Nanomagnets for releasable capture of tumor cells
A. Singh, M.M. Amiji, Northeastern University, US
4:20Isolation and Detection of Cancer Related DNA Nanoparticulate Biomarkers Directly from CLL Patient Blood “Rapid Sample to Sequence Diagnostics”
M.J. Heller, J. Marciniak, A. Sonnenberg, University of California, San Diego, US
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4:30Innovation Spotlights: Pharma & Medical DevicesPotomac 2
Session chair: Lynn Foster, BPT Pharma, US
4:30Language Analysis Tool Detects Cognitive Dysfunction for Early Alzheimer Diagnosis
A. Morrow, University of Minnesota, US
4:37Treating type 2 diabetes using menin inhibitors to regenerate insulin producing beta cells
F. Leu, Novapeutics LLC, US
4:44Integrated Continuous Manufacturing (ICM) of Pharmaceuticals
S. Mascia, CONTINUUS Pharmaceuticals, US
4:51Highly Sensitive Micron Scale Multiple Biomarker Biosensor
C. Yilmaz, Biolom, LLC, US
4:58Personal Health Expert
V. Shusterman, PinMed, US
5:05Flex Technology Inc
W. Krause, Flex Technology Inc, US
5:12Pharmaceutical technology of pharmaceutical composition and pharmacology treatment for enhancement of morphine analgesia and prevention of morphine tolerance
C. Laino, Biotechnology Institute, National University of La Rioja, AR
5:19Modular Biocompatible Materials for Medical Devices and Wound Healing Applications
S. Foster, Diazamed-CSU Ventures, US

Wednesday May 15

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8:30Biosensors: Novel Approaches & InstrumentationAnnapolis 1-2
Session chair: Srinivas Iyer, Bioscience Division, Los Alamos National Laboratory, US
8:30Continuous Flow Real-Time Pcr Platform for High Throughput Environmental Monitoring
T. Ray, A. Hatch, K. Lintecum, S-H Chao, C. Youngbull, Arizona State University, US
8:50Triplet-Triplet Annihilation Upconversion in Water Environment: Biocompatible and Non-invasive All-optical Temperature Sensing for Living Objects
D. Busko, R. Dimitrova, A. Turshatov, Y. Avlasevich, K. Landfester, S. Baluschev, Max Planck Institute for Polymer Research, DE
9:10Influence of metallic, ceramic, and plastic MALDI surface materials on the ionization efficiency and quality of mass spectrometric data
A. Hieke, Stanford University, School of Medicine, US
9:30Multilayer Architectures of Enzymes on Electrodes for Sensorial Application – Influence of the Building Blocks on the Assembly Behaviour
F. Lisdat, Technical University Wildau, DE
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11:00Innovation Spotlights: Pharma & BiotechPotomac 3
Session chair: Belen Martinez-Lopez, CaramelTech, MX, Reviewers: Roche, Sanofi, Merck, Jennifer Gottwald, WARF, US
11:00Roche - Strategic Innovation Interests
M. Wetzel, Roche, US
11:15Sanofi - Strategic Innovation Interests
S. Natesan, Sanofi, US (bio)
11:30Merck - Strategic Innovation Interests
S. Xanthoudakis, Merck, US (bio)
12:00Targeted Drug Delivery System/Keystone Nano
D. Fecko, Penn State Materials Research Institute, US
12:07Novel SiO2-based antioxidant compound with significantly extended life-time and activity
G. Sotiriou, ETH Zurich – ETH transfer (the Technology Transfer Office), CH
12:14Diabetes Control Algorithms and Clinical Trial Software
S. Juncal, UCSB Office of Technology & Industry Alliances, US
12:21Biodegradable Polymer for Biomedical Applications
L. Besemann, University of Minnesota, US
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4:00Innovation Spotlights: Medical DevicesPotomac 1
Session chair: Allen Dines, University of Wisconsin-Madison, US
4:00Fiberoptic Microneedle Device for Convection-Enhanced Thermochemotherapy of Malignant Glioma
C. Rylander, Virginia Tech Intellectual Properties, Inc., US
4:07CANCELED - Operation system of laparoscope using pneumatically driven robotic holder
M. Yamamoto, Japan Technology Group Inc., JP
4:14A high throughput one-step assay for circulating tumor cell detection in whole blood sample
Y. Zu, The Methodist Hospital, US
4:21CereScope™ - A Portable All-in-One Neurological Monitoring System
R. Kern, Optima Neuroscience, Inc., US
4:28Medipacs Mini-Infuser™
M. Banister,, US
4:35Flat Panel X-ray Sources
M. Eaton, Stellarray, US

Special Symposium

This symposium will feature innovative applications-focused research and development in the following focus areas:

Nanoparticles in Imaging Technologies
Non-invasive imaging technologies for the diagnosis of disease typically involve the administration of contrast or signal enhancement agents that facilitate the visualization of organs or the state of a particular disease. Nanotechnology, particularly the development of nanoparticle-based agents, has had a tremendous impact in the design of targeted and specific nanoagents with the potential of homing on a particular area and interrogating for normal or disease processes. Submissions are invited on nanoparticle technologies for the visualization at the molecular or cellular level using magnetic resonance imaging (MRI), optical/fluorescent imaging, X-ray computed tomography (X-ray CT), ultrasound and positron emission tomography (PET), among others.

Clinical/Health Applications
One of the most significant impacts of the nanotechnology revolution is seen in the area of biomolecular analysis, which, as predicted by Feyman, has reached new levels of sensitivity, precision and resolution due to advances in the physical sciences. Submissions are invited on the development of biosensors for clinical and health applications. These may include point of care diagnostics, lab-on-a-chip integration, novel functionalization schemes, and the development of nano-neural interfaces.

Defense Applications
Nanoscale sensing approaches have significant potential for the detection of for threat agents including biological, chemical, and radiological materials. Submissions in this topic area may also address sample formats and novel analytical schemes.

Environmental Applications
There is an increasing demand for sensors to assess and monitor environmental parameters that affect human health including pollutants and pathogens such as viruses and bacteria. Developments in sensor technology are critical for measuring air and water quality and for assessment during remediation efforts. Papers describing novel approaches for sensing in a variety of environmental formats are invited.

Novel approaches and instrumentation
Fundamental to all applications areas are core developments in materials and techniques for nanoscale sensing. Submissions are invited on novel materials, technologies and instrumentation.

Technical Abstract Submission

Please first review the information for authors as well as the abstract preparation guidelines.


Journal Submissions

Nanomedicine Journal

Nanomedicine: Nanotechnology, Biology and Medicine (Nanomedicine)

Nanomedicine NBM publishes articles on all issues related to nanomedicine, including the application of nanoscience and nanotechnology in biology and medicine.

Manuscripts must be directly or closely related to medicine (diagnosis, treatment, monitoring, prognosis and prevention of diseases) and supporting biology, especially understanding biologic mechanisms enabled by nanoscience, -engineering and -technology research, i.e.such as, research of man-made nanoscale objects, materials, and devices that improve medical procedures and outcome.

For consideration into the Nanomedicine: Nanotechnology, Biology and Medicine journal please select the “Submit to Nanomedicine: Nanotechnology, Biology and Medicine” button during the on-line submission procedure.


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