TechConnect World 2017
National SBIR/STTR Conference National Innovation Summit & Showcase Nanotech 2017

Materials for Drug & Gene Delivery

Materials for Drug & Gene Delivery

Abstracts due: February 28, 2017

Technical Abstract Submission

Please first review the information for authors — abstract submission guidelines.

Symposium Co-Chairs

Steven ZulloSteven Zullo
Program Officer, Extramural Science Program, OPESP

Thomas AnchordoquyThomas Anchordoquy
Professor, Skaggs School of Pharmacy and Pharmaceutical Sciences
University of Colorado School of Pharmacy

Key Speakers

Shanta DharSelf-therapeutic Nanoparticles for Atherosclerosis
Shanta Dhar
Assistant Director of Technology and Innovation, Sylvester Comprehensive Cancer Center, Associate Professor, University of Miami

David V. MorrisseyRobust in vivo gene editing in mouse hepatocytes with systemic lipid nanoparticle delivery of CRISPR/Cas9 components
David V. Morrissey
Senior Vice President, Platform and Delivery Technology, Intellia Therapeutics, Inc.

Nathan GianneschiNathan Gianneschi
Associate Professor of Chemistry and Biochemistry

David RampullaDavid Rampulla
Program Director, Division of Discovery Science & Technology
US National Institute for Biomedical Imaging and Bioengineering (NIBIB)

Michelle BradburyMichelle Bradbury
Director, Center of Translation for Nanomedicine & Intraoperative Imaging Program
Cornell University

Hamid GhandehariHamid Ghandehari
Professor, Director of Utah Center for Nanomedicine
University of Utah

Agata ExnerEchogenic Nanobubbles: New opportunities for ultrasound-enhanced drug delivery for cancer therapy
Agata Exner
Professor of Radiology and Biomedical Engineering, Case Western Reserve University

Symposium Sessions

Monday May 15

1:00Biomed Innovation Spotlights: Medtronic, GE

Tuesday May 16

10:30Nanoparticle Drug Delivery and Nucleic Acids
1:30Imaging & Drug Delivery, Theranostics

Wednesday May 17

8:30The Future of Drug & Gene Delivery: Panel Discussion
10:30Intracellular & Organelle Delivery
1:30Peptides, Proteins, & Viral-assisted Drug Delivery
Materials for Drug & Gene Delivery

Symposium Program

Monday May 15

1:00Biomed Innovation Spotlights: Medtronic, GE

Tuesday May 16

10:30Nanoparticle Drug Delivery and Nucleic Acids
10:30Robust in vivo gene editing in mouse hepatocytes with systemic lipid nanoparticle delivery of CRISPR/Cas9 components (invited presentation)
D. Morrissey, Intellia Therapeutics, US
10:55TBA (invited presentation)
A. Almutairi, UC San Diego, US
11:20Programmable Formation of Quantum Dot Lattices with Applications in Biosensing and conditional RNAi Activation
K. Afonin, M. Jones, University of North Carolina, Charlotte, US
11:40Therapeutic RNA interference in vivo - fibrillar nanocarbon mediated delivery
M.R. McDevitt, Memorial Sloan Kettering Cancer Center, US
12:00Role of microRNA-205 in Gemcitabine Resistant Pancreatic Cancer
R.I. Mahato, A.K. Chaudhary, G. Mondal, V. Kumar, K. Kattel, D. Chitkara, A. Mittal, University of Nebraska Medical Center, US
12:20Continuous Production of Polymer Coated Drug Crystals, Particles and Nanoparticles by Hollow Fiber Membrane-based Cooling Crystallization and Anti-solvent Crystallization
K. Sirkar, D. Chen, D. Singh, C. Jin, R. Pfeffer, New Jersey Institute of Technology, US
1:30Imaging & Drug Delivery, Theranostics
1:30Self-therapeutic silica nanoparticles for individualized cancer care (invited presentation)
M. Bradbury, Cornell University, US
1:55Echogenic Nanobubbles: New opportunities for ultrasound-enhanced drug delivery for cancer therapy (invited presentation)
A. Exner, Case Western Reserve University, US
2:20Modulation of Doxorubicin Toxicity Through Nanoparticle-assisted Cellular Delivery
A. Sangtani, E. Petryayeva, M. Wu, K. Susumu, E. Oh, A.L. Huston, G. Lasarte-Aragonés, I.L. Medintz, W.R. Algar, J.B. Delehanty, US Naval Research Laboratory, US
2:40Amphiphile Self-Assembly Theranostic Materials for Drug Delivery and Medical Imaging
C.J. Drummond, X. Mulet, C.E. Conn, C. Fong, M. Moghaddam, S.M. Sagnella, X.J. Gong, J. Zhai, RMIT University, AU
3:00Nano-magnetically targeted drug delivery system for treating Atrial Fibrillation (AF)
A. Harel, NanoMed Targeting Systems Inc., US
3:20Drug and Gene Delivery Programs at the National Institute of Biomedical Imaging and Bioengineering (invited presentation)
D. Rampulla, US National Institute for Biomedical Imaging and Bioengineering (NIBIB), US

Wednesday May 17

8:30The Future of Drug & Gene Delivery: Panel Discussion
10:30Intracellular & Organelle Delivery
10:30TBA (invited presentation)
S. Dhar, University of Miami, US
10:55Impact of Particle Modulus on Vascular-Targeted Drug Delivery In Vitro and In Vivo
M.B. Fish, C.A. Fromen, T.F. Scott, R. Adili, M. Holinstat, O. Eniola-Adefeso, University of Michigan, US
11:15Bilayer coated ureteral stent as drug delivery platform to treat ureteric diseases
W. Lim, G.M. Xiong, T.W. Chong, Y. Huang, S. Venkatraman, Nanyang Technological University, SG
11:35An Integrated Biometric Platform for Evaluation of Targeted Drug Delivery
Y. Liu, Lehigh University, US
G. Wei, X. Gao, X. Li, Y. Lu, J.J. Baldwin, B. Liang, IVIEW Therapeutics Inc., US
12:15Magnetically Targeted Endothelial Cells for Prevention of Vascular Restenosis
B. Polyak, Drexel University, US
1:30Peptides, Proteins, & Viral-assisted Drug Delivery
1:30Recombinant polymers for drug and gene delivery (invited presentation)
H. Ghandehari, University of Utah, US
1:55TBA (invited presentation)
N. Gianneschi, University of California, San Diego, US
2:20Self-navigating drug delivery nanovehicles driven by polyvalent multifunctional phages and their promiscuous proteins
V.A. Petrenko, J.W. Gillespie, Auburn University, US
E.O. Akala, Howard University, US
3:00Platform Reagent Development for the Intracellular Delivery of Therapeutic Peptides
B.C. Evans, C. Lander, C.L. Duvall, Moerae Matrix, Inc., US
3:20Nanodelivery of cerebrolysin reduces depressive stress induced exacerbation of Alzheimer’s disease brain pathology following amyloid-beta peptide infusion
H.S. Sharma, D.F. Muresanu, J.V. Lafuente, R. Patnaik, Z.R. Tian, A. Ozkizilcik, R.J. Castellani, H. Mössler, A. Sharma, Uppsala University, SE
Materials for Drug & Gene DeliveryExpo Hall D & E
Sustained Release of Functional Interleukin-10 Encapsulated within Poly (lactic acid)-b-Poly (ethylene glycol) Nanoparticles Down-regulates Cytokines in Mouse Macrophages Exposed to Chlamydia trachomatis
S. Duncan, S. Dixit, R. Sahu, E. Nyairo, S.R. Singh, V.A. Dennis, Alabama State University, US
Physio-structural and immunological characterization of a PLGA 85/15 encapsulated Chlamydia recombinant MOMP nanovaccine candidate
R. Sahu, S. Dixit, S.R. Singh, V.A. Dennis, Alabama State University, US
Site-Specific Albumination for the Enhanced Serum Half-Life In Vivo
I. Kwon, Gwangju Institute of Science and Technology, KR
Alginate/Montmorillonite nancomposites for the delivery of curcumin
A.R. Ramadan, M. Ahmed, The American University in Cairo, EG
Anodized TiO2 Nanotube Film for Controllable Drug Delivery in the Implant
L. Kerr, H. Jia, Miami University, US
Nanodelivery of cerebrolysin reduces functionalized Gold Nanoparticles induced Blood-brain barrier disruption, brain edema formation and brain pathology
A. Sharma, P.K. Menon, D.F. Muresanu, J.V. Lafuente, A. Nozari, R. Patnaik, A. Ozkizilcik, Z.R. Tian, H. Mössler, H.S. Sharma, Uppsala University, SE
In vitro targeting behaviors of Folate-conjugate Pluronic F127/poly (lactic-co-glycolic) nanoparticles
X.Y. Xiong, Jiangxi Science and Technology Normal University, CN
Conjugation of anticancer drugs with novel PEG-containing nanocarrier provides circumvention of drug-resistance mechanisms in vitro and protects of general toxicity in vivo
L. Коbylinska, R. Panchuk, N. Skorohyd, Y. Senkiv, P. Heffeter, W. Berger, N. Boiko, N. Mitina, A. Zaichenko, R. Lesyk, B. Zіmenkovsky, R. Stoika, G.S. Vari, Danylo Halytsky Lviv National Medical University, UA
Amphiphilic (Lipid-Substituted) Cationic Polymers for siRNA Therapy of Leukemias
B. Landry, J. Valencia-Serna, H. Uludag, University of Alberta, CA
Novel Nano-biomaterials for Inhibition of Respiratory Syncytial Virus
S. Joshi, Alabama State University, US
SERS Detection on GABA absorption with using Modified Gold-chitosan Nanoparticles by MPA
B. Wang, I-. Kang, Gachon University, KR
Tunable Non-Viral Vector For Efficient Delivery Of Nucleic Acid
S.K. Kottarath, M. Bhat, A.K. Dinda, S. Mitra, All India Institute of Medical Sciences, IN
Neuroprotective effects of cerebrolysin in exacerbation of blood-brain barrier breakdown, neuropathology and upregulation of nitric oxide synthase and hemeoxygenase in diabetes and hypertension after heat stroke
D.F. Muresanu, A. Sharma, J.V. Lafuente, A. Nozari, R. Patnaik, A. Ozkizilcik, Z.R. Tian, H. Mössler, H.S. Sharma, Iuliu Hațieganu University of Medicine and Pharmacy, RO
TiO2-nanowired delivery of cerebrolysin thwarts exacerbation of sleep deprivation induced decline in regional brain derived neurotrophic factor, brain pathology and behavioral dysfunctions following emotional stress
A. Sharma, D.F. Muresanu, J.V. Lafuente, A. Nozari, R. Patnaik, A. Ozkizilcik, Z.R. Tian, H. Mössler, H.S. Sharma, Uppsala University, SE
Development of Zein Nanoparticles with Covalently Linked and Physically Entrapped Folic Acid as Targeting Nanoagents
T. Chuacharoen, C.M. Sabliov, Suan Sunandha Rajabhat University, TH
Ecofriendly synthesis, characterization and antimicrobial activity of silver nanoparticles
S. Jain, Alabama State University, US
PLGA Nanocapsules Inside of Collagen Nanofibers for Release of Paclitaxel as Agent of Control the Restenosis in Drug Eluting Stents
L. Agudelo, G. Colmenares, R. Pinal, L. Hoyos, Universidad Pontificia Bolivariana, CO
miRNA Expression Analysis in HEp-2 Cells after Gold Nanorod Application
A. Montgomery, S. Bawage, A. Chaudhary, S.R. Singh, K. Vig, Alabama State University, US
Application of a Next Generation Hand Held Antimicrobial Cold Plasma Technology
H. Kim, S. Izadjoo, V. Marcel, H. Truong, M. Izadjoo, Trideum Biociences and ChiScan LLC, US
Positively charged Ag-dendron conjugates: Stability enhanced AgNPs for biomedical applications
T.J. Cho, J. Liu, V.A. Hackley, National Institute of Standards and Technology, US
In Vitro Genetic Transfection of COS-7 Cancer Cells Using RAW 264.7 Macrophages
R. Upadhya, Johns Hopkins School of Medicine, US

Biocompatible materials with nano-scale structure hold great promise for controlled and targeted delivery and half-life extension of both small-molecule drugs and various classes of biologics, such as peptides, proteins, plasmid DNA and synthetic oligodeoxynucleotides. Promising delivery systems include microcapsules, liposomes, macromolecular conjugates, nanoparticles, dendrimers, and biological stuctures such polypeptides, benign viruses and bacteriophages. This symposium will focus on commercially promising new materials and approaches.

Topics & Application Areas

  • Controlled Release & Half Life Extension
  • Biologic Targeting & Delivery
  • Polymer-Based Delivery
  • Nanoparticle-Based Targeting & Delivery
  • Mitochondrial Drug Delivery
  • Novel Delivery Systems
  • Nanomedicine Clinical Trials: Challenges & Results
  • Other

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Platinum Sponsors

Silver Sponsors

Corporate Acceleration Partners
Church & Dwight
Eastman Chemical
Lockheed Martin
Owens Corning

Technology Development Partners
Clemson University
Innovate Hawaii
Iowa State University
KYUNGPOOK National University
National University of Singapore
New Jersey Innovation Institute
SungKyunKwan University
University Of Minnesota

Supporting Partners
American Elements
Angel Capital Associates
Arrowhead Center
Asia Nano Forum
Bilat USA
Diplomacy Matters
Explore Nano
Graphene Council
Journal of Nanobiotechnology
Taylor Francis CRC
Texas Nanotech Initiative
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TechConnect World 2017

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