Amplification-free liquid biopsy by fluorescence approach

J. Uhd, M. Taskova, A. Okholm, K. Astakhova
University of Southern Denmark,
Denmark

Keywords: liquid biopsy, ctDNA, fluorescence, diagnostics, bioimaging

Summary:

Diagnostics of cancer associated ctDNA, BRAF V600E, KRAS G12D and KRAS G13D respectively. By the use of modern fluorescence microscopy and fluorescently labeled mutation specific LNA/DNA probes. Which resulted in a mutation specific detection.