Titanium implants are commonly coated with hydroxyapatite, facilitating bone cell integration (osseointegration). The current method for manufacturing hydroxyapatite coatings produces a surface that does not adequately encourage osseointegration, with poor in vivo stability. We have developed a novel one-step manufacturing process that produces a highly osseointegrative, robust hydroxyapatite coating.
Primary Application Area: Medical Devices
Technology Development Status: Concept
FIGURES OF MERIT
Value Proposition: Our process creates robust ultra-porous biocompatible hydroxyapatite coatings that promote superior bone cell integration and cell penetration. This project is in the early stages, and we are currently exploring mechanisms through which the attachment to the implant can be further enhanced in order to address device reliability. The simplicity of the coating manufacturing process ensures that the cost of implementing this technology in full-scale manufacture is unlikely to be a barrier to uptake.
Companies in the implant market have struggled to incorporate superior osseointegration technologies due to the physical stress applied to such coatings during implant attachment (by screwing, hammering etc.). As a result, fairly resilient but biologically inferior smooth plasma-sprayed hydroxyapatite coatings are industry standard for implants. Note that even these coatings don’t always stick to the metal perfectly, causing failures. Implant failures are very costly to patients, insurers and health care systems. Current data indicates our coating techniques address these shortcomings.
Organization Type: Academic/Gov Lab
Showcase Booth #: 525
GOVT/EXTERNAL FUNDING SOURCES
External Funding to Date: ANUCV Discovery Translation Fund