On-chip and Label-free Glucose Sensing Using Mid-Infrared Waveguides

P.T. Lin
Texas A&M University,
United States

Keywords: diabetes, glucose detection, label-free, lab-on-a-chip

Summary:

A chip-scale glucose sensor was developed using nitride optical waveguides. The label free detection was conducted at λ = 2.70 - 2.81 µm and 3.50 - 3.70 µm because these spectral regions overlap with the characteristic O-H and C-H stretch absorptions while being transparent to nitride. For a glucose covered mid-IR waveguide strong intensity attenuation was found at λ > 2.73 µm and a detection limit better than 0.5 ng is experimentally demonstrated.