Synthetic Immunotherapy Platform for Vaccine Development
Avalia Immunotherapies has developed a platform technology to deliver therapeutic cancer vaccines that activate the most powerful tumor-fighting cells in the body. The vaccines are discrete synthetic compounds that deliver both a cancer-specific peptide antigen and a powerful immune system activator simultaneously to dendritic cells.
Nanoparticle Formulation of Oral Paclitaxel
This invention is a novel nanoparticle formulation that utilizes natural plant derivatives to increase the solubility and permeability of paclitaxel and allow for oral administration. The derivatives replace harmful chemical and synthetic solvents normally required for paclitaxel to be absorbed and can potentially reduce the side effects of drug treatment.
Baton Rouge, LA
Nanoparticle Matrix for Delivery of Natural Bioactive Components
This technology is a method to synthesize polymer matrices that entrap bioactive compounds such as lutein. Lutein can come from sources like yellow flowers and corn. The matrix has tunable properties that can greatly enhance the stability of entrapped compounds that can be used as antioxidants.
Meros drug and biologic delivery polymers
Meros drug delivery polymers provide enhanced solubility, stability and sustained release of pharmaceuticals for multiple routes of administration. Bio-compatible and biodegradable, the polymers self-assemble into drug-loaded micelles, which can be further processed by lyophilisation or spray-drying, suitable for formulation using conventional methods and facilities.
Use of Titanium-Based Materials as Bactericides
The use of metal ions to control bacterial infections remains of interest as drug-resistant bacteria are becoming increasingly common and dangerous to human health. This technology provides safe and effective metal-titanate bacterial inhibitors.
Inulin Nanofibers with Prebiotic and Antibacterial Activity
Fabrication of electrospun nanofibers from natural materials using Electrospinning technique and investigating the microbiological effect of the electrospun nanofibers versus their solutions. The natural material used was Inulin, and it was mixed with FDA approved synthetic polymer (PVA), to aid inulinâ€™s electrospinning capability.
Nanoparticles-based combinatorial therapy for breast cancer
The present invention entails the development of NanoParticles (NPs)-based combinatorial therapy composed of Doxorubicin (DOX) loaded on core-shell silver/ polymeric (PVA, PEG, and PVP) NPs. This NPs-based combinatorial therapy has potent anticancer activity aimed at achieving maximum therapeutic efficacy, while minimizing DOXâ€™s dose and systemic toxicity.
Boron-based integrin-linked kinase (ILK) inhibitors for therapeutic and diagnostic uses
Novel compounds and a method of treatment to reduce cyst growth in Polycystic Kidney Disease (PKD). The compounds target a key cellular pathway involved in aberrant proliferation in PKD, cancer, and neurological disorders. Compounds are synthesized using a unique approach to improve drug efficacy, specificity, solubility and cellular uptake.
Novel LKB1-AMPK Activator for Therapeutic Use in Polycystic Kidney Disease
The invention consists of a novel compound and method for treating Polycystic Kidney Disease utilizing a novel liver kinase B1 (LKB1) activator to stimulate AMP-activated protein kinase (AMPK), leading to inhibition of mTOR-mediated cellular proliferation and chloride-dependent fluid secretion, key components of cyst growth.
Compounds for the Treatment of Alzheimer's Disease by Inhibiting Interaction of Amyloid Beta Peptide and Amyloid binding alcohol dehydrogenase (ABAD)
A novel class of small molecule AÎ²-ABAD interaction inhibitors for the treatment of Alzheimer's Disease
Essential Amino Acids for improving patient outcome
Essential Amino Acids for improving patient mobility post-total knee arthroplasty surgery.
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