Traumatic brain injury repair with neurotropic factors and coral scaffold
A breakthrough method for nervous tissue repair using a graft system for regenerative medicine of injured brain and spinal cord, with implications for therapy of tissue loss following neurodegenerative diseases. It's based on synchronous usage of two components: a novel material mixture and a bioactive coral skelton scaffold
FLOWPAD is a generic microfluidics platform that responds to the need for miniaturization and integration of laboratory procedures into lab-on-chip devices. Depending of the design of the consumable microfluidic cartridge, FLOWPAD is able to address biology, healthcare, security or environmental applications
A portable, hand-held device that can detect and identify bacteria in fluids (water, blood, urine etc.) in under 30 minutes as opposed to the current standard of 24-48 hours. It uses a patent-pending silicon technology developed at Yale University to detect single bacteria directly, without any need for culture growth.
Diagnosis of Kidney diseases
Diagnosis of kidney diseases via urinary proteins This technology is designed to easily detect various kidney diseases including chronic renal failure, acute renal failure, IgA nephropathy, diabetic nephropathy, and so on. In addition, this technology evaluates prognosis of kidney diseases.
Solid-State Fermentation for Production of Succinic Acid from Renewable Biomass
This technology relates to the use of solid-state fermentation to produce succinic acid from sugarcane bagasse. Succinic acid produced via this method is highly concentrated (~80%) and incurs much lower purification costs compared to submerged ferementation where energy intensive purifications eg distillation is used for purification.
Chemotherapy wafer to treat oral cancer topically
Our ChemoThin Wafer (CTW) is a polymeric mesh that hold chemotherapy nano-particles. upon hydration, it releases the nano particles along with other excipients directly into the tumor. The CTW is unidirectional mucoadhesive wafer that remain in place and can be removed after one hour of appliction.
Transdermal Microneedle Sensors
We are developing a wearable point of care diagnostic system capable of monitoring an individualâ€™s local and systemic physiological state based on transdermal microneedle sensors. Such a minimally invasive sensor has applications in home health care, sports medicine, and defense of the warfighter.
High Performance Nanoparticle-Based MRI Contrast Agent
We have developed a novel nanoparticle-based MRI contrast agent that shows efficacy an order of magnitude higher than current clinical MRI contrast agents, and is safe for use in patients with kidney problems for whom current clinical MRI contrast agents are restricted for use.
Multiplexed genome editing by natural transformation for accelerated evolution of microbes (MuGENT)
Researchers from Tufts have developed a novel method for multiplex genome editing in naturally competent microbes. This method offers unprecedented speed of evolution of traits and phenotypes and can become the foundation for the rapid development of custom-designed microbes which can be used in the broad spectrum of applications.
Nanoscale Coordination Polymers (NCP) for Platinum â€“Resistant Ovarian Cancer
NCP drug delivery platforms have the potential to overcome many drawbacks of existing drug delivery systems such as low drug loading. The NCP offers controlled drug cargo release, modular surface structures contribute to NCP targeting, lower drug dosage, and siRNA for added gene therapy in one formulation.
MRSA Antibody Therapeutic Simultaneously Treats and Vaccinates Against Reinfection
A monoclonal antibody that demonstrates effectiveness as both a treatment and vaccine for Staphylococcus aureus infections. The therapeutic antibody vaccine is effective in treating methicillin-resistant S. aureus (MRSA) infection by enabling bacterial killing and generating a protective immune response that prevents recurrence.
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