TechConnect Innovation Program

Multiplexed genome editing by natural transformation for accelerated evolution of microbes (MuGENT)

Tufts University Tech Transfer, MA, United States

TECHNOLOGY SUMMARY

Researchers from Tufts have developed a novel method for multiplex genome editing in naturally competent microbes. This method offers unprecedented speed of evolution of traits and phenotypes and can become the foundation for the rapid development of custom-designed microbes which can be used in the broad spectrum of applications.

Primary Application Area: Biotech & Biological Sciences

Technology Development Status: Prototype

Technology Readiness Level: TRL 3

FIGURES OF MERIT

Value Proposition: This new technology overcomes the limitations of existing methods by broadening the scope of microorganisms that can be targeted. The number of mutations types that can be introduced into the genome is significantly higher than for competitive approaches, making the technology an invaluable tool for metabolic and phenotypic engineering applications.

SHOWCASE SUMMARY

Organization Type: Academic/Gov Lab

National Innovation Awardee

Showcase Booth #: 16M - 16T

Website: http://techtransfer.tufts.edu

GOVT/EXTERNAL FUNDING SOURCES

Government Funding/Support to Date:

Primary Sources of Funding: Federal Grant

Looking for: Both Funding and Development Partners