TechConnect Innovation Program

Nanoparticle-based Therapy for the Targeted Treatment of Metastatic Breast Cancer

University of Central Florida, Florida, United States

TECHNOLOGY SUMMARY

This nanotechnology is being developed for the treatment of metastatic breast cancer. The nanoparticle-peptide complex is designed to specifically target breast cancer cells, disrupt their ability to migrate, and induce cell death. Delivery of the complex in vivo resulted in significant tumor regression in a breast cancer mouse model.

Primary Application Area: Biotech & Biological Sciences

Technology Development Status: Prototype

Technology Readiness Level: TRL 3

FIGURES OF MERIT

Value Proposition: UCF’s technology overcomes many of the challenges associated with current breast cancer treatments. It features a cost effective nanotechnology-based platform for concentrated, targeted delivery of a proprietary therapeutic peptide. The peptide is easy to synthesize and targets a metastatic cancer phenotype, minimizing non-specific effects on healthy cells.

SHOWCASE SUMMARY

Organization Type: Academic/Gov Lab

Showcase Booth #: 724

Website: tt.research.ucf.edu

GOVT/EXTERNAL FUNDING SOURCES

Government Funding/Support to Date: NIH/NIGMS 02/01/2008 - 01/31/2013

Primary Sources of Funding: Federal Grant

Looking for: Both Funding and Development Partners