TechConnect Innovation Program

Sleep deprivation in Military and Alertness are reduced by H-290/51 pretreatmentfor

Uppsala University, Uppland, Sweden


Sleep deprivation in military during combat operation is quite common. Long term sleep deprivation leads to mental dysfunction and decreases alertness and functional activity. Also behavioral disturbances could occur in military personnel for long time sleep deprivation that could be fatal.

Primary Application Area: Biotech & Biological Sciences

Technology Development Status: Concept

Technology Readiness Level: TRL 4


Value Proposition: Help support to develop this technology so that we could develop this product for commercial use that could benefit our soldiers and civilians alike.


Organization Type: Early-stage Startup (Seed)

Showcase Booth #: 636



Government Funding/Support to Date: DOD could be a very useful organization to support and develop this concept. NIH could also help in this venture. I am looking to develop this research further with new knowledge and to test this idea further using biomarkers in this circumstances to find a reliable tool to attenuate sleep deprivation induced problems in our soldiers when they are engaged in combat operations. This is also not well known whether the effects of sleep deprivations are altered following nanoparticles intoxication or mild head injury. These aspects must be determined. In our previous study we found that the drug dose require to be enhanced when rats are intoxicated with nanoparticles. Since our soldiers are often intoxicated with silica, carbon and other nanoparticles, these factors may also affect their sleep pattern. Thus the dose response of H-290/51 is needed to be investigated in details. This requires support from other organizations.

Primary Sources of Funding: Corporate Partner, University

Looking for: Both Funding and Development Partners