Nanosensors: Tools for Achieving Sustainable Nanotechnology
Omowunmi (Wummi) Sadik
Professor of Bioanalytical, Materials & Environmental Chemistry
State University of New York at Binghamton
The Research Group of Dr. Sadik consists of graduate students, postdoctoral researchers and visiting scholars. Our research interests lie in the area of Sensors, Environmental, Electrochemical and Materials Chemistry.
In sensors, we seek to better understand molecular recognition at electrochemical interfaces and to utilize the knowledge gained in developing novel chemical and biosensors. One central focus in this research area is the development of novel instrumentation, new measurement approaches and their application to solving problems in biology, energy and the environment. We have designed prototyped and patented novel U-PAC biosensor instrument and a completely automated sampling system requiring minimal user interaction.
In environmental chemistry, our goal is to create sustainable nanotechnology through the development of novel remediation and environmental monitoring technologies. We have developed novel approaches to catalytically convert Chromium (VI) to Chromium (III) using nanostructured materials. Our nanotoxicity research focuses on a series of engineered nanomaterials and natural phenolic estrogens for their ability to affect the viability and proliferation of mammalian cells. To assess and distinguish the cytotoxic effect of individual estrogens we are using MTT, cell-based assays and fluorescence measurements. The induction of the cell-specific apoptotic process is being examined by fluorescence microscopy after treatment of cells with fluorescent dyes.
In advanced materials, we focus on the development of flexible membranes, inherently conducting polymers and novel bioconjugated materials. Our Group has extensive expertise in electrochemistry focusing on interfacial reaction at metal-metal surfaces using electroless plating. We have specifically studied the mechanism of electroless gold, nickel and cobalt using dimethylaminoborane (DMAB). We employ a combination of surface, structural and morphological techniques to monitor the interfacial reactivity and plating rates, including electrochemical quartz crystal microbalance (EQCM), scanning electron microscopy (SEM), energy-dispersive spectroscopy (EDS), and X-ray photoelectron (XPS) analysis. We have also developed EQCM based mass sensor arrays for correlating the bath chemistry with the overall plating quality on industrial wirebond samples.