Chromatic Microfluidic Chip for Label-free Protein Detection Based on Colloidal Photonic Crystal

M. Li, W. Shen, Y. Song
Institute of Chemistry, Chinese Academy of Sciences, CN

Keywords: microfluid, immunoassay, colloidal crystal, photonic crystal

Summary:

Integrating photonic crystal (PC) into the microfluidic system has attracted immense interest for its novel functions. However, it is still a great challenge to fabricate PC microfluidic chip rapidly with complex functions. In this work, a direct-writing colloidal PC microchannel was firstly achieved by inkjet printing and was used for the surface-tension-confined microfluidic immune assay. PC channels with different structure colors have been successfully integrated on one chip. The fabricated chip has advantages of rapid fabrication, quick fluidic transport and can monitor the fluidic fluxion by naked eyes. Utilizing this PC microfluidic chip, a colorimetric label-free immune assay was realized without nonspecific adsorption interference of the target.