s-SWCNT Sensor Platform for Pathogen Detection and Physiological Monitoring

J. Lee, H. Cho, S. Somu, H. Lee, A. Gu, A. Busnaina
Center for High-rate Nanomanufacturing, US

Keywords: carbon nanotubes, conductance based sensors, physiological monitoring, pathogens

Summary:

We have developed a novel, flexible s-SWCNT conductance based sensor platform for instantaneous measurement of pathogens in the environment and for monitoring physiological parameters of human body for applications in the wearable electronic skin and environmental monitoring. These two terminal sensors comprises of highly sensitive and selectively functionalized s-SWCNTs serving as the channel with an active area of <10 μm2. s-SWCNTs channels were fabricated using a novel offset printing process while the electrodes were made using conventional lithography process. The selective functionalization is conducted employing an in-house developed enzyme-immobilization technique. The choice of functionalization molecule is determined by the chemo- bio analyte that is to be detected. We show that D-glucose, L-lactate, Urea, Oxytetracycline (OTC), E. coli, and Adenovirus were detected with very high sensitivity, selectivity, stability and repeatability. This developed biosensor platform detects D-glucose, L-lactate, Urea, Oxytetracycline (OTC), E. coli, and Adenovirus over a wide range (0~300 μM, 0~100 mM, 0~100 mg/dL, 0-150 μg/L, 0-107 cfu/ml, and 0-107 pfu/ml respectively) in less than 5 secs making them suitable for various applications.