Treating type 2 diabetes using menin inhibitors to regenerate insulin producing beta cells

F. Leu
Novapeutics LLC, US

Keywords: menin, beta cells regeneration, diabetes

Summary:

We are developing a novel small molecule diabetes therapeutic to enhance endogenous insulin producing beta cell regeneration in diabetes patients. We are determining the impact of the identified lead compounds (CDH1‐2) on beta cell regeneration and to optimize improved compounds based on the crystal structure of drug target menin.