Monday June 18, 2012, 9:00 am - 5:00 pm, Santa Clara, California
The extraordinarily large surface area on the nanoparticles presents diverse opportunities to place functional groups on the surface. Particles can be created that can expand/contract with changes in pH, or interact with anti-bodies in special ways to provide rapid ex-vivo medical diagnostic tests. Important extensions have been made in combining inorganic materials with polymers and in combining different classes of polymers together in nanoparticle form.
Advanced analytical techniques allow us to measure structure at ever-decreasing length scales. Computer simulations of the events occurring during particle formation have also benefited us in developing control strategies to produce structured particles.
The second part focuses on characterization (analysis and verification) and the wide range of application areas of economic importance. The objectives are to:
Polymeric nanoparticles are predominantly prepared by wet synthetic routes. Several industrial processes will be described. Emphasis will be placed on the type of polymers and morphology structures that can be synthesized using each process. Controlled radical polymerization will be explored for their ability to provide structural control of polymer chains.
A brief overview of suspension and dispersion-precipitation polymerization relevant to nanoparticles is included. Emulsion polymerization methods are provided to allow a more detailed presentation of reactive and non-reactive pathways to nanoparticle formation.
A section of the course is dedicated to polymeric nanoparticles characterization. Of critical importance is the measurement of particle size, bulk and surface chemical composition. Importantly, the internal structure of the particles can be measured by combinations of microscopy and thermal analysis. All techniques will be presented for their utility toward polymeric nanoparticles characterization.
The last part of the course is focused on the applications of polymeric nanoparticles. The most traditional field of application is waterborne paints, adhesives, and coatings. The details of some formulation and application issues will be presented. Of more recent emergence is the field of redispersible latices and pressure sensitive adhesives.
A recent boom in the range of application of polymeric nanoparticles is the sector of biotechnology, and more specifically biomedical products. These include the critical delivery of sensitive drugs and medical diagnostics. Last but not least, polymeric nanoparticles have found their ways in EMO devices.
All through the course practical problems will be solved both individually and in groups.
Donald C. Sundberg, Ph.D., Director of the Nanostructured Polymers Research Center in the Materials Science Program at the University of New Hampshire, Durham, NH, USA. Professor Sundberg has been working in the field of emulsion polymers for over 44 years. He received a bachelor’s degree in chemical engineering from Worcester Polytechnic Institute in Massachusetts and his Ph.D. from the University of Delaware. He spent 5 years working on impact modifiers for ABS polymers with the Monsanto Company prior to pursuing an academic career. His research interests include polymerization kinetics in solution, bulk and emulsion systems, interfacial science and polymer morphology control, diffusion in polymers, micro- and nano-encapsulation, coatings, and controlled release technology.
Yvon Durant, Ph.D., Research Associate Professor of Materials Science at the University of New Hampshire and Director of the Advanced Polymers Laboratory, Durham, NH, USA. Dr. Durant earned a degree in chemistry and chemical engineering in from Ecole Nationale Supérieure de Chemie de Montpellier, received his Ph.D. in polymer chemistry from the Université Claude Bernard, Lyon I in France and an MBA from the University of New Hampshire. He has worked as both scientist and project leader in the Polymer Laboratory within BASF AG, Germany and has been an active industrial consultant. Dr Durant’s areas of research interests include polymer dispersions, drug delivery, nanostructured polymers, and polymerization kinetics.