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Nanoskin Bacterial cellulose structured- Towards the development of regenerative medicine

G.M. Olyveira, L.M.M. Costa, P. Basmaji

Keywords: bionanocomposites, regenerative medicine


Bacterial cellulose (BC) has established to be a remarkably versatile biomaterial and can be used in wide variety of applied scientific endeavors, especially for medical devices. In fact, biomedical devices recently have gained a significant amount of attention because of an increased interest in tissue-engineered products for both wound care and the regeneration of damaged or diseased organs. Due to its unique nanostructure and properties, microbial cellulose is a natural candidate for numerous medical and tissueengineered applications. Moreover, the nanostructure and morphological similarities with collagen make BC attractive for cell immobilization and cell support. The architecture of BC materials can be engineered over length scales ranging from nano to macro by controlling the biofabrication process. It has unique properties that make it an exciting candidate as a vascular graft material: strength, good integration into host tissue, and flexibility of production in various shapes and sizes.In this article, the structural features of microbial cellulose and its properties are discussed with AFM and SEM and novel biomimetic bionanocomposites from BC/collagen and BC/chitosan are presented for artificial blood vessels.
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