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Fabrication of Magnetic Poly (ethylene glycol) Hydrogels Blocks Using Microfluidic System for Cell Patterning Techniques

H.-Y. Chang, C.-Y. Fu, C.-Y. Lin, T.-P. Wang
National Tsing Hua University, TW

Keywords: cell patterning, microfluidic system, PEG-DA

Abstract:

In this study, we developed a novel technique called magnetic hydrogel-based cell patterning (MHCP) to easily achieve heterotypic cell patterning in both of multi-well plate-based methods and microfluidic system. We also demonstrated that the material of magnetic hydrogel and the processes of MHCP produced negligible effects on cell viability. The 2-D heterotypic cell patterning and layer-by-layer 3-D tissue reconstruction could be applied as more complex models in disease research models and tissue engineering.
 
 
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