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Assessing the Manufacturing and Environmental Life Cycle of Engineered Nanoparticles Using the NexION 300TM ICP-MS

C. Stephan
PerkinElmer, CA

Keywords: nanoparticles, single particle ICP-MS, TGA


The use of nanoparticles in consumer products shows a tremendous increase over the past years. The National Institute of Standard and Technologies reported that nanotechnology-based consumer products are currently entering the market at a rate of 3 or 4 per week and it is estimated that $2.6 trillion in manufactured goods will contain nanotechnology by 2014. As active compounds these products contain ZnO for surface protection, TiO2 for sun screen, Ag for anti-bacterial purposes and quantum dots for medical imaging, disease detection, solar cells and photovoltaic’s, only to name a few applications. Therefore, in spite of their beneficial properties, possible risks for humans and the environment need to be thoroughly investigated and multiple key characteristics need to be assessed. Detailed information about the quantity, shape, size, distribution, structure, composition, surface charge and functionality need to be studied and addressed in order to perform an appropriate and reliable risk assessment. To achieve this, many advanced instrumentation have to be employed from Thermogravimetric Analysis (TGA), Differential Scanning Calorimetry (DSC), Field Flow Fractionation (FFF) to Inductively Coupled Plasma Optical Emission or Mass Spectrometry (ICP-OES or ICP-MS) among others. This talk will take you on a tour addressing the role of advanced instrumentation with a focus on Single Particle-ICP-MS in unveiling key characteristics that will help assess the manufacturing and environmental impact of Engineered Nanomaterials.
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