Immunotherapy with nanoparticles targeting ion channels: research and application challenges

Laura Conforti

Laura Conforti

Associate Professor, Pathobiology and Molecular Medicine

University of Cincinnati

Our laboratory is interested in ion channels and the membrane mechanisms that regulate the activation and function of human lymphocytes. Ion channels control calcium homeostasis and downstream associated effector functions. The main interests of the lab span from studying the function and regulation of ion channel in normal lymphocytes to determining ion channel abnormalities in cancer and autoimmunity. The techniques used in the laboratory include, but are not limited to, electrophysiology (patch-clamp) and fluorescence and confocal microscopy. Furthermore, nanotechnology methods are currently applied with the goal of developing novel therapeutic agents.

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