MWCNTs and SWCNTs based Nanocomposites for Cartilage and Bone Tissue Regeneration

L.G. Zhang, B. Holmes
The George Washington University, US

Keywords: carbon nanotubes, bone, cartilage, nanocomposite


Cartilage and bone defects, which are caused by a variety of reasons such as traumatic injuries, osteoarthritis, osteoporosis or bone cancers, represent common and severe clinical problems. Developments in nanotechnology and tissue engineering have provided promising ways to repair and replace damaged cartilage and bone. Since human cartilage and bone extracellular matrices are nanostructured, novel biomimetic nanomaterials are desirable for cartilage and bone regenerations. Thus, the objective of this research is to create novel biologically inspired tissue engineered cartilage and bone scaffolds via two types of carbon nanotubes (i.e., magnetically treated single-walled carbon nanotubes, B-SWCNTs and H2 treated multi-walled carbon nanotubes, MWCNTs) and nanocrystalline hydroxyapatite (nHA) (Figure 1) for improving bone and cartilage regeneration.