Application of superparamagnetic nanoparticles for magnetically guided release of anti-cancer drug: An Ivvivo study on Rats

J. Choubey, M. Swami
Rani Durgawati Vishwavidyalya, Jabalpur, IN

Keywords: gelatin, iron oxide, nanoparticles, doxorubicin, drug targating

Summary:

By using appropriate magnetic parameters, 50-80% of the injected nanoparticles could be targeted, thus eliminating systemic distribution and subsequent toxicity of the entrapped agent. In this report we present data on the use of magnetic nanoparticles bearing doxorubicin in the treatment of subcutaneous tumors in rats.