Materials for Drug & Gene Delivery

Materials for Drug & Gene Delivery

Symposium Chair

Steven  ZulloSteven Zullo
Program Director, Division of Discovery Science and Technology
NIBIB/NIH

Confirmed Invited Speakers

Kevin SillDevelopment of a Stable Micelle for Drug Delivery in Oncology
Kevin Sill
Chief Science Officer, Intezyne
Gayle E.  WoloschakTiO2-DNA Nanocomposites for Imaging and Therapeutic Applications
Gayle E. Woloschak
Robert E. Lurie Comprehensive Cancer Center Feinberg School of Medicine, Northwestern University
Juliane  NguyenNovel Zwitterionic Liposome Approaches to Lipid Based Nucleic Acid Delivery
Juliane Nguyen
Ph.D., Deutsche Forschungsgemeinschaft Fellow, Department of Bioengineering and Therapeutic Sciences, School of Pharmacy, University of California, San Francisco
Adah  AlmutairiThe Art of Falling Apart: Exploiting Nanomaterial Disassembly for Medicine and Pharmacy
Adah Almutairi
Professor, Laboratory for Bioresponsive Materials, University of California, San Diego
Suzie Hwang  PunDevelopment of peptide-based polymers for gene transfer to the CNS
Suzie Hwang Pun
Associate Professor of Bioengineering, University of Washington
James  TaylorMicrofluidic technology enables scalable manufacture of limit-size lipid nanoparticles (lsLNP): size matters for the next generation of therapeutic drug delivery systems
James Taylor
CEO and Co-Founder, Precision NanoSystems
Ann-Marie BroomeTargeting Laser Treatment to Inaccessible Tumors Using Nanoparticle Drug Delivery Vehicles
Ann-Marie Broome
Associate Professor, Medical University of South Carolina
Mark HayesNew Liposomes for Cancer and Chronic Disease Treatment
Mark Hayes
Co-Founder & Senior Scientist, ZoneOne Pharma Inc
Mercedeh  KhajavikhanThresholdless Nanoscale Lasesrs
Mercedeh Khajavikhan
Staff Researcher, UCSD

Symposium Sessions

Tuesday June 19

10:30 Materials for Drug & Gene Delivery Keynotes I
12:30 Networking Lunch - Expo
1:30 TechConnect IP Partnering: Biotech & Biosciences
1:30 Materials for Drug & Gene Delivery Keynotes II
2:45 TechConnect IP Partnering: Medical, Pharma, Personal Care
4:00 Financing Emerging Technology Commercialization
4:30 Expo Reception and Poster Session I (4:30 - 6:30)
 Materials for Drug & Gene Delivery

Wednesday June 20

11:00 Materials for Drug & Gene Delivery III
12:30 Networking Lunch - Expo
1:00 NNI - Director’s Networking Session, National Nanotechnology Coordination Office
1:30 Exhibit and Poster Session II
 Materials for Drug & Gene Delivery
3:30 Materials for Drug & Gene Delivery IV
5:30 TechConnect Innovation Showcase Reception
6:00 CTSI Utility Technology Challenge Awards and Reception

Thursday June 21

10:00 National Nanotechnology Initiative Triennial Review
12:30 National Innovation Showcase - Networking Lunch (available for purchase)
2:30 TechConnect Start-Up Partnering: Medical, Pharma, Personal Care
4:00 TechConnect Start-Up Partnering: Biotech, Biomaterials & Biosciences
4:00 TechConnect National Innovation Showcase, Reception & Poster Session III

Symposium Program

Tuesday June 19

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10:30Materials for Drug & Gene Delivery Keynotes IGrand Ballroom D
Session chair: Steven Zullo, NIBIB National Institutes of Health, US
10:30Development of a Stable Micelle for Drug Delivery in Oncology
K. Sill, Intezyne, US (bio)
11:00Development of peptide-based polymers for gene transfer to the CNS
S.H. Pun, University of Washington, US (bio)
11:30The Art of Falling Apart: Exploiting Nanomaterial Disassembly for Medicine and Pharmacy
A. Almutairi, University of California, San Diego, US (bio)
12:00Novel Zwitterionic Liposome Approaches to Lipid Based Nucleic Acid Delivery
J. Nguyen, C. Walsh, M. Motion, F.C. Szoka, University of California, San Francisco, US (bio)
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12:30Networking Lunch - ExpoExpo Hall AB
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1:30TechConnect IP Partnering: Biotech & BiosciencesRoom 212
Session chair: Lynn Foster, BPT Pharma, Reviewers: Scott Carter, Latham & Watkins, Julia Ljubimova, Cedars-Sinai Medical Center, US
1:30New Compound Activates Broad Spectrum Lung Immunity
N. Zelver, Montana State University Technology Transfer, US
1:40Novel Agents to Enhance Tolerance to an Immunogen
N. Zelver, Montana State University Technology Transfer, US
1:50Glycine N-methyltransferase (GNMT) Animal model and use thereof
Y.M. Chen, National Yang-Ming University, TW
2:00Novel Single Dose Sterilant for Male and Female Companion and Feral Animals
R. Kulkani, University of Kansas Center for Technology Commercialization, US
2:10A Novel Protein Folding System
R. Kulkani, University of Kansas Center for Technology Commercialization, US
2:20Non-Viral Nanoparticle-Based Delivery System
M. Malhotra, McGill University, CA
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1:30Materials for Drug & Gene Delivery Keynotes IIGrand Ballroom D
Session chair: Steven Zullo, NIBIB National Institutes of Health, US
1:30TiO2-DNA Nanocomposites for Imaging and Therapeutic Applications
G.E. Woloschak, Northwestern University, US (bio)
2:00Microfluidic technology enables scalable manufacture of limit-size lipid nanoparticles (lsLNP): size matters for the next generation of therapeutic drug delivery systems.
J. Taylor, Precision Nanosystems, US
2:30Targeting Laser Treatment to Inaccessible Tumors Using Nanoparticle Drug Delivery Vehicles
A.-M. Broome, Case Western Reserve University, US (bio)
3:00Thresholdless Nanoscale Lasers
M. Khajavikhan, University of Minnesota, US
3:30New Liposomes for Cancer and Chronic Disease Treatment
C. Noble, ZeroOne Pharma, Inc., US
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2:45TechConnect IP Partnering: Medical, Pharma, Personal CareRoom 207
Session chair: Belen Martinez-Lopez, CaramelTech, MX, Reviewers: Schuyler Corry, Invtitrogen, Mark Wittman, Beyond Lucid Technologies, Cece Gassner, City of Boise, US
2:45NCap - NanoPorous Materials for Sustained Release
W. Daniell, NanoScape AG, DE
2:55Medical Nano-magnetic Drug Guidance
A. Harel, NanoMed Targeting Systems Inc., US
3:05Universal Optofluidic Chip for Ultra-Sensitive Raman Analysis of Liquid
S. Mak, University of Toronto, CA
3:15Next generation single dose vaccine adjuvants
S. Niewiesk, The Ohio State University, US
3:25Double Clad Fiber Coupler Allowing 3D Endoscopy
T. Martinuzzo, Univalor, CA
3:35Nanogold Assays for Direct Detection of Nucleic Acids of High Burden Infections
H. Azzazy, The American University in Cairo, EG
3:45A Liquid Crystal Polymer (LCP) Membrane MEMS Sensor for Flow Rate and Flow Direction Sensing, Medical and Environmental Applications
L.M. Sim, Industry Liaison Office, National University of Singapore (NUS), SG
3:55Fluorescent and Luminescent Labels for Diagnostic Imaging and Sensitive Detection of Biopolymers
S. Pillai, New Jersey Institute of Technology, US
4:05Leukocyte coping capacity: stress-testing at your fingertips
D. Sarphie, Oxford MediStress Ltd, UK
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4:00Financing Emerging Technology CommercializationRoom 203
Session chair: Tom Klein, Greenberg Traurig, US
-P. Dhingra, NanoStellar, US
-B. Segal, Lockheed Martin, US
-B. Horangic, North Bridge, US
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4:30Expo Reception and Poster Session I (4:30 - 6:30)Expo Hall AB
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Materials for Drug & Gene Delivery
-Controlled- Release Antibiotic Nanoparticles for Cranial Transplantation and Bone Grafting
A.N. Adusumilli, S. Dammalapati, P.K.-L. Fu, Governors State University, US
-Surface Functionalized Multicomponent Envelope Type Nanosystems for Improved Gene Delivery
D. Pozzi, V. Orlando, G. Augusti Tocco, S. Biagioni, F. Cardarelli, A. Bifone, G. Caraccioloa, Sapienza University of Rome, IT
-Nanoscale iron trimesate metal organic framework as potential platform for active nucleoside analogues delivery
V. Agostoni, T. Chalati, P. Horcajada, H. Willaime, P. Couvreur, R. Anand, S. Monti, C. Serre, R. Gref, UMR CNRS 8612, FR
-Nanoparticles of iron trimesate metal organic framework (MIL100) for drugs encapsulation and delivery, comparisons between two different syntheses.
H. Willaime, V. Agostoni, P. Horcajada, C. Serre, R. Gref, Université Paris-Sud, FR
-Nanoparticle platform for therapeutic siRNA delivery to HER2 positive breast cancer
W. Ngamcherdtrakul, J. Morry, T. Sangvanich, R. Lee, Z. Hu, S. Gu, J. Gray, W. Yantasee, Oregon Health and Science University, US
-Preparation and evaluation of some carriers for the immobilization of β-Galactosidase
N.Y.F. Almehbad, Faculty of Education for Female Teachers Najran, SA
-A Novel Single Step Method of Synthesizing Large Unilamellar Liposomes for Biomedical Applications
S.M. Phapal, P. Sunthar, Indian Institute of Technology Bombay, IN
-Multidrug resistance protein P-gp interaction with nanoparticles (fullerenes and carbon nanotubes) to assess drug delivery to the CNS: a molecular docking study
S. Shityakov, C. Förster, University of Würzburg, DE
-Cell penetrating peptide mediated delivery of has-miRNA-29b to promote mesenchymal stem cell differentiation into osteogenic lineage
J.S. Suh, J.Y. Lee, Y.S. Choi, C.P. Chung, Y.J. Park, Seoul National University, KR
-Metal Oxide Nanoparticle-Induced Changes in 20S Proteasome Activity
C.A. Falaschetti, T. Paunesku, S.S. Chou, M.H. Song, J-T Jang, V.P. Dravid, J. Cheon, G.E. Woloschak, Northwestern University, Feinberg School of Medicine, US

Wednesday June 20

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11:00Materials for Drug & Gene Delivery IIIGreat America 3
Session chair: Steven Zullo, NIBIB National Institutes of Health, US
11:00Controlling the Intracellular Distribution of Agents with Core/Shell Particles Made from Particle Blends
K.K. Tran, H. Shen, University of Washinton, US
11:20Multifunctionalized gold nanoparticles for controlled drug-release by non-linear excitation
V. Voliani, F. Ricci, G. Signore, R. Nifosì, S. Luin, F. Beltram, Center for nanotechnology innovation @NST, Istituto italiano di tecnologia and Scuola normale superiore, IT
11:40Multifunctional Gold Nanorod-Based Drug/SiRNA Nanocarriers for Targeted Neuroendocrine Cancer Therapy
Y. Xiao, R. Jaskula-Sztulb, H. Chen, S. Gong, University of Wisconsin-Madison, US
12:00Targeted Nucleoprotein Nanodevices for Diagnosis and Delivery
E. Singer, K. Munson, T. Wilson, S. Smith, Beckman Research Institute of the City of Hope, US
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12:30Networking Lunch - ExpoExhibit Hall AB
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1:00NNI - Director’s Networking Session, National Nanotechnology Coordination OfficeExhibit Hall A
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1:30Exhibit and Poster Session IIExhibit Hall AB
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Materials for Drug & Gene Delivery
-Understanding Adhesion of Bioactive Polymers on Hydrophobic and Hydrophilic Surfaces.
V. Vyas, B.D. Huey, University of Connecticut, US
-Supramolecular assemblies of cisplatin and polyelectrolytes: preparation, characterization and activity against cancer cells
D.B. Vieira, V. Kim, D.F.S. Petri, C.F.M. Menck, A.M. Carmona-Ribeiro, Universidade de São Paulo, BR
-Orally Delivered Polymeric nanoparticles of Lopinavir: Development and Statistical optimization, in vitro and ex vivo studies
G. Joshi, K.K. Sawant, M S University of Baroda, IN
-Nanostructured cellulose materials: adsorption of antibiotics onto cellulose fibers functionalized with glycidylmethacrylate for the manufacturing of antibacterial fabrics
E. Vismara, G. Torri, A. Valerio, G. Graziani, A. Montanelli, L. Melone, Politecnico di Milano, IT
-Properties of Hydrophobized Chitosan-Insulin Nanoparticles with different hydrophobic chain sizes.
E. Robles, E. Villar, J. Juárez, P. Taboada, M.-G. Burboa, M. Alatorre, V. Mosquera, M.-A. Valdez, Universidad de Sonora, MX
-Self Assembled Nanostructures of Triblock Co-polymer and Plasmid DNA for Gene Delivery
H.K. Daima, S. Shankar, P.R. Selvakannan, S.K. Bhargava, V. Bansal, RMIT University, AU
-In vitro anticancer activity of poly(3-hydroxybutyrate) nanoparticles loaded with antitumor drug Paclitaxel
S.G. Yakovlev, A.P. Bonartsev, D.V. Bagrov, Yu.M. Efremov, A.P. Boskhomdzhiev, E.V. Filatova, P.V. Ivanov, T.K. Makhina, G.A. Bonartseva, A.N.Bach’s Institute of Biochemistry Russian Academy of Sciences, RU
-Nanospray Dryer Employed in Nanoencapsulated Production
A.M. Oliveira, N.N.P. Cerize, K.L. Guimarães, J.G.R. Poco, A.S. Tunussi, D.C.S. Patto, Institute of Technological Research – IPT, BR
-Sequential Surface Functionalization by Polyoxometalates and Lysine Renders Non-toxic Gold Nanoparticles Strong Antibacterial Agents
H.K. Daima, P.R. Selvakannan, S.K. Bhargava, V. Bansal, RMIT University, AU
-Encapsulation and Characterization of BSA in PLA-PEG Nanoparticles as a Model for Chlamydia trachomatis rMOMP-278 Protein Nanovaccine Delivery System
M. Taha, S.R. Singh, C. Moore, R. Agee, V.A. Dennis, Alabama State University, US
-Counting and Sizing Protein Aggregates Down to 0.15 micron Using New Focused Beam Light Scattering Technology
P. O’Hagan, D.F. Nicoli, K. Hasapidis, Particle Sizing Systems, US
-Surfactant Effect on Intercellular Transport of DNA, Proteins, and Electrolytes
D. Assan, X. Gao, J.C.K. Lai, S.W. Leung, Idaho State U, US
-Drug diffusion transport models for nanoporous material
A. Ziemys, M. Milosevic, M. Ferrari, M. Kojic, The Methodist Hospital Research Institute, US
-Development of PHEMA-Chitosan nanospheres and encapsulation of RSV-F DNA vaccine
E. Eroglu, A.B. Waffo, V.A. Dennis, S.R. Singh, Alabama State University, US
-Nanoparticle Analysis with a Tunable Pore Sensor for Monitoring of Drug Delivery Systems
Y. Ganor, Izon Science Ltd, US
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3:30Materials for Drug & Gene Delivery IVGreat America 2
Session chair: Steven Zullo, NIBIB National Institutes of Health, US
3:30Drug Delivery with Light-Activated Gold-Coated Liposomes
G.V. Orsinger, S.J. Leung, S.S. Knights, J.D. Williams, M. Romanowski, University of Arizona, US
3:50Lyophilisomes: novel protein capsules as drug delivery system
E. van Bracht, P.J. Geutjes, R.G. Wismans, E. Oosterwijk, T.H. Kuppevelt, W.F. Daamen, Radboud University Nijmegen Medical Centre, NL
4:10Electrically-Controlled Drug Release System to Assist Wound Healing
S. Zhu, J. Mbugua, M. Chase, J. Maskrod, J.H. Jung, T. Nicholson III, E. Fabrizio, R. Mercado, Crosslink, US
4:30Designing Responsive Materials with Chemically Amplified Sensitivity to NIR light
N. Fomina, C. McFearin, M. Sermsakdi, J. Morachis, A. Almutairi, University of California at San Diego, US
4:50Dual Modal Gene Expression and Silencing Using Viral/Nonviral Chimeric Nanoparticles for Synergistic Gene Therapy
S.K. Cho, T. Luu, S. Wong, Y.J. Kwon, UC Irvine, US
5:10Triple protection delivery system for retinaldehyde: Preparation, skin penetration and controlled release at the hair follicles.
P. Supmuang, S. Wanichwecharungruang, Chulalongkorn University, TH
5:30Electrospun Nanofibrous Scaffold for Controlled Drug Delivery
V. Leung, R. Hartwell, E. Faure, H. Yang, A. Ghahary, F. Ko, University of British Columbia, CA
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5:30TechConnect Innovation Showcase ReceptionExpo Hall CD
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6:00CTSI Utility Technology Challenge Awards and ReceptionExpo Theater 1
Session chair: Patti Glaza, Arsenal Venture Partners, US

Thursday June 21

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10:00National Nanotechnology Initiative Triennial ReviewGreat America 1
Session chair: Erik Svedberg, National Materials and Manufacturing, National Academies, US
10:00NNI Town Hall Meeting
E. Svedberg, National Nanotechnology Initiative, US
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12:30National Innovation Showcase - Networking Lunch (available for purchase)Expo Hall CD
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2:30TechConnect Start-Up Partnering: Medical, Pharma, Personal CareExpo Theater 2
Session chair: Paul Prendergast, Merchant & Gould, US
2:30Topical Skin Adhesive
W.B. Jeon, IntuitiveMediCorp, KR
2:40Nano-Magnetic drug targeting
A. Harel, NanoMed Targeting Systems Inc., US
2:50Leukocyte coping capacity: stress-testing at your fingertips
D. Sarphie, Oxford MediStress Ltd, US
3:00Reagent-free nanobiomimetic electrochemical sensing platform
E. Chen, Advanced Biomimetic Sensors, Inc., US
3:10Magnetic nanotechnology for targeted cancer treatment
T. Mitrelias, Cavendish NanoTherapeutics, UK
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4:00TechConnect Start-Up Partnering: Biotech, Biomaterials & BiosciencesExpo Theater 2
Session chair: Paul Prendergast, Merchant & Gould, US
4:00Laser Transmission Spectroscopy
C. Tanner, LightSprite, LLC, US
4:10Novel Shape Memory foam devices for neurovascular and other vascular applications
S. Biswas, Shape Memory Therapeutics, US
4:20Low-power, high brightness, high-resolution LED Light
S. Kang, Lux World Co., Ltd., KR
4:30Disruptive wireless silicon platform for disposable wireless healthcare sensors
S. Magar, HMicro, Inc., US
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4:00TechConnect National Innovation Showcase, Reception & Poster Session IIIExpo Hall CD

Special Symposium

Biocompatible materials with nano-scale structure hold great promise as controlled release reservoirs for delivery of both small-molecule drugs and various classes of biomacromolecules, such as peptides, proteins, plasmid DNA and synthetic oligodeoxynucleotides. Promising delivery systems include microcapsules, liposomes, macromolecular conjugates, nanoparticles, dendrimers, and biological nanostuctures such benign viruses and bacteriophages. This symposium will focus on success stories and reports of exciting new nanostructured materials and approaches for drug and gene delivery.

Topics & Application Areas

  • Targeting at Molecular, Cellular & Higher Levels
  • Novel Delivery Systems
  • Modes of Entry
  • Controlled Release Systems
  • Microcapsules
  • Liposomes
  • Polymer-based delivery systems
  • Antibody Targeting
  • Protein/Peptide Delivery
  • Pharmacodynamics
  • Nanomedicine clinical trials: challenges & results
  • Other

Journal Submissions

Nanomedicine Journal

Nanomedicine: Nanotechnology, Biology and Medicine (Nanomedicine)

Nanomedicine: Nanotechnology, Biology and Medicine (Nanomedicine) is a newly established, international, peer-reviewed journal published quarterly. Nanomedicine publishes basic, clinical, and engineering research in the innovative field of nanomedicine. Article categories include basic nanomedicine, diagnostic nanomedicine, experimental nanomedicine, clinical nanomedicine, and engineering nanomedicine, pharmacological nanomedicine.

For consideration into the Nanomedicine: Nanotechnology, Biology and Medicine journal please select the “Submit to Nanomedicine: Nanotechnology, Biology and Medicine” button during the on-line submission procedure.

Nanoparticle Research

Journal of Nanoparticle Research

Selected Nanotech Proceedings papers will be reviewed and invited into a Special Issue of Journal of Nanoparticle Research. The journal disseminates knowledge of the physical, chemical and biological phenomena and processes in nanoscale structures.

For consideration into this Special Issue of Journal of Nanoparticle Research, please select the “Submit to Journal of Nanoparticle Research” button during the on-line submission procedure.

 

Sponsor & Exhibitor Opportunities

 Exhibit and Showcase
 Become a Sponsor

Please contact: Denise Lee


Program Tracks

Fabrication & Characterization

Advanced Materials

Electronics & Microsystems

Medical & Biotech

Energy & Environment

Business & Partnering

 

2012 TechConnect Corporate Acceleration Partners:

AC-NET
Applied Materials
Austin_Energy
BASF
BayerMaterialScience
bp
ConstellationEnergy
DOW
Fraunhofer TechBridge
Hitachi
Honda
IBM
Kauffman Foundation
Kodak
Lam
Lockheed Martin
MWV
nationalgrid
NortheastUtilities
novaris
Panasonic
PPG
Samsung
schlumberger
Shell_GameChanger
siemens
SK Innovation
SouthernCalEdison
Toray

In Partnership with

NSTI


Sponsorship Opportunities: Contact Denise Lee

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