Biosensing, Diagnostics & Imaging

Symposium Co-Chairs

Srinivas IyerSrinivas Iyer
Bioscience Division
Los Alamos National Laboratory
Manuel PerezManuel Perez
Assistant Professor of Chemistry and Nanoscience Technology
University of Central Florida

Confirmed Invited Speakers

Hedi MattoussiFunctional nanocrystals as tunable platforms for imaging and sensing
Hedi Mattoussi
Professor, Department of Chemistry & Biochemistry, Florida State University
Kirk D. RectorKirk D. Rector
Materials Chemistry, Sensing and Imaging Team Leader
Los Alamos National Laboratory
Zhen  ChengNovel Gold Nanoparticles for Cancer Photoacoustic Imaging
Zhen Cheng
Assistant Professor, Radiology - Nuclear Medicine, Stanford University
Jim  WernerJim Werner
Technical Staff Member
Center for Integrated Nanotechnologies, LANL

Symposium Sessions

Tuesday June 19

10:30 Biosensing, Diagnostics and Imaging I
12:30 Networking Lunch - Expo
1:30 TechConnect IP Partnering: Biotech & Biosciences
2:00 Biosensing, Diagnostics and Imaging II
2:45 TechConnect IP Partnering: Medical, Pharma, Personal Care
4:00 Financing Emerging Technology Commercialization
4:30 Expo Reception and Poster Session I (4:30 - 6:30)
 Biosensing, Diagnostics & Imaging
 Cancer Nanotechnology

Wednesday June 20

8:30 Cancer Nanotech I
10:30 Cancer Nanotech II
12:30 Networking Lunch - Expo
1:00 NNI - Director’s Networking Session, National Nanotechnology Coordination Office
1:30 Exhibit and Poster Session II
 Cancer Nanotechnology
3:30 Cancer Nanotech III
5:30 TechConnect Innovation Showcase Reception
6:00 CTSI Utility Technology Challenge Awards and Reception

Thursday June 21

10:00 National Nanotechnology Initiative Triennial Review
10:30 Biosensing, Diagnostics and Imaging III
12:30 National Innovation Showcase - Networking Lunch (available for purchase)
1:30 Biosensing, Diagnostics and Imaging IV
2:30 TechConnect Start-Up Partnering: Medical, Pharma, Personal Care
4:00 TechConnect Start-Up Partnering: Biotech, Biomaterials & Biosciences
4:00 TechConnect National Innovation Showcase, Reception & Poster Session III

Symposium Program

Tuesday June 19

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10:30Biosensing, Diagnostics and Imaging IGreat America J
Session chair: Srinivas Iyer, Los Alamos National Laboratory & Manuel Perez, University of Florida, US
10:30Functional nanocrystals as tunable platforms for imaging and sensing
H. Mattoussi, Florida State University, US (bio)
11:00Time-Resolved Three Dimensional Molecular Tracking in Live Cells
J. Werner, Los Alamos National Lab, US (bio)
11:30Novel Gold Nanoparticles for Cancer Photoacoustic Imaging
Z. Cheng, Stanford University, US
12:00Time-lapse Chemical Microscopy using Intracellular Chemical Nanosensors
K. Rector, Los Alamos National Lab, US (bio)
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12:30Networking Lunch - ExpoExpo Hall AB
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1:30TechConnect IP Partnering: Biotech & BiosciencesRoom 212
Session chair: Lynn Foster, BPT Pharma, Reviewers: Scott Carter, Latham & Watkins, Julia Ljubimova, Cedars-Sinai Medical Center, US
1:30New Compound Activates Broad Spectrum Lung Immunity
N. Zelver, Montana State University Technology Transfer, US
1:40Novel Agents to Enhance Tolerance to an Immunogen
N. Zelver, Montana State University Technology Transfer, US
1:50Glycine N-methyltransferase (GNMT) Animal model and use thereof
Y.M. Chen, National Yang-Ming University, TW
2:00Novel Single Dose Sterilant for Male and Female Companion and Feral Animals
R. Kulkani, University of Kansas Center for Technology Commercialization, US
2:10A Novel Protein Folding System
R. Kulkani, University of Kansas Center for Technology Commercialization, US
2:20Non-Viral Nanoparticle-Based Delivery System
M. Malhotra, McGill University, CA
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2:00Biosensing, Diagnostics and Imaging IIGreat America J
Session chair: Srinivas Iyer, Los Alamos National Laboratory & Manuel Perez, University of Florida, US
2:00Gold Nanoparticles as a Surface to Immobilize Gadolinium-Hydroxypyridinone (HOPO) Complexes for Use a Magnetic Resonance Imaging (MRI) Contrast Agents
P.J. Klemm, P.J. Straney, M.N. Keyser, J.E. Millstone, K.N. Raymond, UC Berkeley, US
2:20A Metallofullerene Nanoparticle Platform for Imaging and Treatment of Glioblastoma Multiforme Tumors
H.C. Dorn, J. Zhang, P. Fatouros, M.D. Shultz, J.D. Wilson, Virginia Polytechnic Institute and State University, US
2:40Magneto-plasmonic Nanoplatforms for Enhanced Bioimaging and Photothermal Cancer Therapy
A. Kopwitthaya, T.Y. Ohulchanskyy, M. Jeon, W-C. Law, Q. Xie, R.R. Chada, X. Xue, E.P. Furlani, C. Kim, P.N. Prasad, University at Buffalo (SUNY), US
3:00Encapsulation of nanoparticles with multifunctional, cross-linkable diblock copolymers for biomedicine
C. Schmidtke, J. Ostermann, H. Tran, E. Pöselt, H. Kloust, J. Niehaus, S. Becker, A. Kreuziger, K. Werner, A. Pietsch, H. Weller, University of Hamburg, DE
3:20Fully integrated, multi-parametric flow cytometry chip using single layered three-dimensional (3D) hydrodynamic focusing
A.A. Nawaz, X. Mao, T.J. Huang, Pennsylvania State University, US
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2:45TechConnect IP Partnering: Medical, Pharma, Personal CareRoom 207
Session chair: Belen Martinez-Lopez, CaramelTech, MX, Reviewers: Schuyler Corry, Invtitrogen, Mark Wittman, Beyond Lucid Technologies, Cece Gassner, City of Boise, US
2:45NCap - NanoPorous Materials for Sustained Release
W. Daniell, NanoScape AG, DE
2:55Medical Nano-magnetic Drug Guidance
A. Harel, NanoMed Targeting Systems Inc., US
3:05Universal Optofluidic Chip for Ultra-Sensitive Raman Analysis of Liquid
S. Mak, University of Toronto, CA
3:15Next generation single dose vaccine adjuvants
S. Niewiesk, The Ohio State University, US
3:25Double Clad Fiber Coupler Allowing 3D Endoscopy
T. Martinuzzo, Univalor, CA
3:35Nanogold Assays for Direct Detection of Nucleic Acids of High Burden Infections
H. Azzazy, The American University in Cairo, EG
3:45A Liquid Crystal Polymer (LCP) Membrane MEMS Sensor for Flow Rate and Flow Direction Sensing, Medical and Environmental Applications
L.M. Sim, Industry Liaison Office, National University of Singapore (NUS), SG
3:55Fluorescent and Luminescent Labels for Diagnostic Imaging and Sensitive Detection of Biopolymers
S. Pillai, New Jersey Institute of Technology, US
4:05Leukocyte coping capacity: stress-testing at your fingertips
D. Sarphie, Oxford MediStress Ltd, UK
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4:00Financing Emerging Technology CommercializationRoom 203
Session chair: Tom Klein, Greenberg Traurig, US
-P. Dhingra, NanoStellar, US
-B. Segal, Lockheed Martin, US
-B. Horangic, North Bridge, US
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4:30Expo Reception and Poster Session I (4:30 - 6:30)Expo Hall AB
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Biosensing, Diagnostics & Imaging
-Novel and Rapid Assay for HIV Diagnosis and Drug Screening
C. Esseghaier, C. Tlili, A. Ng, M. Zourob, Institut National de la Recherche Scientifique (INRS), CA
-Continuous Sensing of blood by dark-field microscopy and surface-enhanced Raman Spectroscopy
A.-I. Henry, B. Sharma, L.B. Sagle, R.P. Van Duyne, Northwestern university, US
-Illuminating Epidermal Growth Factor Receptor Densities on Filopodia through Plasmon Coupling
J. Wang, S.V. Boriskina, H. Wang, B.M. Reinhard, Boston University, US
-Nanocomposites of Nanocrystalline Cellulose for Biosensors Applications
V. Incani, C. Danumah, Y. Boluk, University of Alberta, CA
-Cytotoxicity and genotoxicity evaluations for superparamagnetic iron oxide nanoparticles coated with various functional groups
J. Lee, S. Hong, F. Sun, J. Lee, J. Kim, Pusan National University, KR
-Gold nanoparticles as a tool to detect UTI and their cytotoxic effects in DU-145 cells
P. Vedantam, G. Huang and T.R. Tzeng, Clemson University, US
-Spectroscopic Ultra-Trace Detection of Nitroaromatic Gas Vapor on Rationally Designed Two-Dimensional Nanoparticle Cluster Arrays
J. Wang, L. Yang, S. Boriskina, B. Yan, B.M. Reinhard, Boston University, US
-A sensing properties study on miniature Au/SnO2 gas sensor for hydrogen sulfide detection
B.W. Chang, S.J. Ding, R.L.C. Chen, HungKuang University, TW
-CarouCELL – a novel compact submerged perfusion bioreactor for drug screening and tissue engineering
M. Foss, D.Q.S. Le, Aarhus University, DK
-An Integrated Microfluidic Real-Time PCR System for Pathogen Detection
L. Zhu, L. Li, D. An, M. Wang, L. Zhang, Y.K. Wang, Z. Li, Y. Liu, G. Zhang, F. Lin, University of Manitoba, CA
-DNA detection using Laser Transmission Spectroscopy
F. Li, A.R. Mahon, M.A. Barnes, S. Egan, J. Feder, D.M. Lodge, C.-T. Hwang, R. Schafer, S.T. Ruggiero, C.E. Tanner, University of Notre Dame, US
-Simultaneous Measurement of Nitric Oxide and Oxygen Dynamics during Myocardial Ischemia Reperfusion of Rat
G.J. Lee, S.W. Kang, O.K. Kim, S.K. Kim, J.H. Shin, H.K. Park, Kyung Hee University, KR
-The Effects of Temperature and Relative Humidity on the Stability of Paper-immobilized Antibodies
J. Wang, B. Yiu, J. Obermeyer, C.D.M. Filipe, J.D. Brennan, R.H. Pelton, McMaster University, CA
-Design of a noninvasive blood glucose Sensor
J.M. Wang-Roveda, D. Nguyen, H.V. Nguyen, MIAO LLC, US
-Ultra-sensitive label-free electrical detection of proteins by field-effect transistor based on chemically derived graphene
N.-E. Lee, D-J Kim, I.Y. Sohn, J-H Jung, O.J. Yoon, J-S Park, Sungkyunkwan University, KR
-An Ultra-compact X-ray Source for Medical Applications
C. Camara, M. Valentine, G. Jimenez, D. Kamkar, D. Cuadra, K. Beverly, B. Lucas, A. Belz, Tribogenics, Inc, US
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Cancer Nanotechnology
-Immunodiagnosis for cervical cancer using antibody-gold nanoparticle conjugate
S. Tapaneeyakorn, C. Thepthai, N. Apiwat, T. Dharakul, National Science and Technology Development Agency, TH
-Dual gold nanoparticles-enhanced sensitivity of colorimetric immunoassay for the visual detection of cervical cancer biomarker
W. Maneeprakorn, N. Apiwat, S. Tapaneeyakorn, T. Dharakul, National Nanotechnology Center, National Science and Technology Development Agency, TH
-Activation of Inflammasomes by Tumor Cell Death Mediated by Gold Nanoshells
H.T. Nguyen, K.K. Tran, B. Sun, H. Shen, University of Washington, US
-Targeted Cancer Therapy by Immunoconjugated Gold-Gold Sulfide Nanoparticles Using Protein-G as a Cofactor
X.H. Sun, G.D. Zhang, D. Patel, A.M. Gobin, University of Louisville, US
-Supermagnatic Iron Oxide Nanoparticles Toxicity to Mammalian Cells
K. Vig, P. Tiwari, A. Parveen, V. Rangari, S.R. Singh, Alabama State University, US
-Development of theranostic nanoparticles with the ability to break extracellular cellular matrix for enhanced nanoparticle delivery
X. Guo, W. Qian, A. Wang, L. Yang, Emory University, US

Wednesday June 20

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8:30Cancer Nanotech IGrand Ballroom A
Session chair: Mansoor Amiji, Northeastern University, US
8:30Top Down Nanotechnology for Cancer Diagnostics
R. Bashir, University of Illinois, US (bio)
9:15Nanoscience Strategies for the Design and Ultra Sensitive Readout of Dense Immunodiagnostic Platforms
M. Granger, University of Utah, US (bio)
9:45Fluid Biopsy in Solid Tumors, how HD-CTCs can provide real-time insights into cancer
P. Kuhn, Scripps Physics Oncology Center; The Scripps Research Institute, US (bio)
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10:30Cancer Nanotech IIGrand Ballroom A
Session chair: Mansoor Amiji, Northeastern University, US
10:30Nanomedicine for early detection of cancer and cancer therapy response monitoring
D. Akin, Stanford University, US (bio)
11:00Cell-Nanomaterial Interaction: Implications in Cell-Signaling and Targeted Therapy
R. Kudgus, Mayo Clinic, US (bio)
11:30Therapeutic gene silencing in vivo using RNA interference
A. Sood, M.D. Anderson Cancer Center, US
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12:30Networking Lunch - ExpoExhibit Hall AB
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1:00NNI - Director’s Networking Session, National Nanotechnology Coordination OfficeExhibit Hall A
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1:30Exhibit and Poster Session IIExhibit Hall AB
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Cancer Nanotechnology
-Mn-Zn Ferrite and Photosensitizer Co-Loaded Cancer Theranostic Agent for Magnetic Resonance Imaging and Photodynamic Therapy
S.-M. Lai, M.-D. Yang, M.-J. Tung, P.-S. Lai, National Chung Hsing University, TW
-Copper complexes loaded on nanostructured TiO2 materials as citotoxic agents of cancer cells
T. Lopez, E. Ortiz, P. Guevara, E. Gómez, Instituto Nacional de Neurologia y Neurocirugia, MX
-Electrospun 5-fluorouracil loaded bovine serum albumin-polyvinylpyrrolidone nanofibers
U.E. Illangakoon, N.P. Chatterton, G.R. Williams, T. Nazir, London Metropolitan University, UK
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3:30Cancer Nanotech IIIGrand Ballroom A
Session chair: Mansoor Amiji, Northeastern University, US
3:30Nano-Therapeutics for Blocking Multiple Targets: New Age for Combination Cancer Treatments
J. Ljubimova, Cedars-Sinai Medical Center, US
4:00Vascular and tumor imaging using targeted viral nanoparticles
M. Manchester, University of California, San Diego, US (bio)
4:30Systemic Responses to Targeted Nanoparticle Imaging and Theranostic Agents
L. Yang, Emory University School of Medicine, US (bio)
5:00Translational Cancer Nano-Medicine: Multimodal Strategies to Overcome Tumor Drug Resistance
M. Amiji, Northeastern University, US
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5:30TechConnect Innovation Showcase ReceptionExpo Hall CD
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6:00CTSI Utility Technology Challenge Awards and ReceptionExpo Theater 1
Session chair: Patti Glaza, Arsenal Venture Partners, US

Thursday June 21

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10:00National Nanotechnology Initiative Triennial ReviewGreat America 1
Session chair: Erik Svedberg, National Materials and Manufacturing, National Academies, US
10:00NNI Town Hall Meeting
E. Svedberg, National Nanotechnology Initiative, US
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10:30Biosensing, Diagnostics and Imaging IIIRoom 204
Session chair: Srinivas Iyer, Los Alamos National Laboratory & Manuel Perez, University of Florida, US
10:30Rapid and sensitive detection of an intracellular pathogen in human peripheral leukocytes with hybridizing magnetic relaxation nanosensors
M. Perez, University of Central Florida, US (bio)
11:00PLGA-PEG multifunctional nanoparticles for simultaneous drug delivery and imaging by MRI and fluorescence microscopy
A. Fornara, A. Chiavarino, J. Qin, M.S. Toprak, M. Muhammed, YKI - Institute for Surface Chemistry, SE
11:20A Nanopore Biomimetic Device Quantitatively Detects Early Stage Cancer Cells; a Contour Map Multiple Variable Correlation Method Assesses the Heat of Cancer Cells Released
E.T. Chen, Y. Shen, J. Thornton, C. Ngatchou, S-H. Duh, P.T. Kissinger, Advanced Biomimetic Sensors, Inc., US
11:40Novel three-dimensional porous film for single-cell microarray applications
S. Ranjan, Z. Yong, National University of singapore, SG
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12:30National Innovation Showcase - Networking Lunch (available for purchase)Expo Hall CD
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1:30Biosensing, Diagnostics and Imaging IVGreat America J
Session chair: Srinivas Iyer, Los Alamos National Laboratory & Manuel Perez, University of Florida, US
1:30Sample Preparation by On-Chip Dielectrophoretic Separation and Concentration of Viable, Non-Viable and Viable but Not Culturable (VBNC) Escherichia coli
M. Packard, M. Shusteff, E. Alocilja, Michigan State University, US
1:50Ultralow Detection of Bio-markers using Gold Nanoshells
D. Patel, G. Zhang, X. Sun, A.M. Gobin, R.S. Keynton, University of Louisville, US
2:10Breath acetone monitoring by portable Si:WO3 gas sensors
M. Righettoni, A. Tricoli, S. Gass, A. Schmid, A. Amann, S.E. Pratsinis, ETH Zurich, CH
2:30Disposable Coded Low Signal-Noise Ratio Single Cell Impedance Cytometry
S. Emaminejad, M. Javanmard, R.W. Dutton, R.W. Davis, Stanford Genome Technology Center, US
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2:30TechConnect Start-Up Partnering: Medical, Pharma, Personal CareExpo Theater 2
Session chair: Paul Prendergast, Merchant & Gould, US
2:30Topical Skin Adhesive
W.B. Jeon, IntuitiveMediCorp, KR
2:40Nano-Magnetic drug targeting
A. Harel, NanoMed Targeting Systems Inc., US
2:50Leukocyte coping capacity: stress-testing at your fingertips
D. Sarphie, Oxford MediStress Ltd, US
3:00Reagent-free nanobiomimetic electrochemical sensing platform
E. Chen, Advanced Biomimetic Sensors, Inc., US
3:10Magnetic nanotechnology for targeted cancer treatment
T. Mitrelias, Cavendish NanoTherapeutics, UK
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4:00TechConnect Start-Up Partnering: Biotech, Biomaterials & BiosciencesExpo Theater 2
Session chair: Paul Prendergast, Merchant & Gould, US
4:00Laser Transmission Spectroscopy
C. Tanner, LightSprite, LLC, US
4:10Novel Shape Memory foam devices for neurovascular and other vascular applications
S. Biswas, Shape Memory Therapeutics, US
4:20Low-power, high brightness, high-resolution LED Light
S. Kang, Lux World Co., Ltd., KR
4:30Disruptive wireless silicon platform for disposable wireless healthcare sensors
S. Magar, HMicro, Inc., US
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4:00TechConnect National Innovation Showcase, Reception & Poster Session IIIExpo Hall CD

Special Symposium

This symposium will feature innovative applications-focused research and development in the following focus areas:

Nanoparticles in Imaging Technologies
Non-invasive imaging technologies for the diagnosis of disease typically involve the administration of contrast or signal enhancement agents that facilitate the visualization of organs or the state of a particular disease. Nanotechnology, particularly the development of nanoparticle-based agents, has had a tremendous impact in the design of targeted and specific nanoagents with the potential of homing on a particular area and interrogating for normal or disease processes. Submissions are invited on nanoparticle technologies for the visualization at the molecular or cellular level using magnetic resonance imaging (MRI), optical/fluorescent imaging, X-ray computed tomography (X-ray CT), ultrasound and positron emission tomography (PET), among others.

Clinical/Health Applications
One of the most significant impacts of the nanotechnology revolution is seen in the area of biomolecular analysis, which, as predicted by Feyman, has reached new levels of sensitivity, precision and resolution due to advances in the physical sciences. Submissions are invited on the development of biosensors for clinical and health applications. These may include point of care diagnostics, lab-on-a-chip integration, novel functionalization schemes, and the development of nano-neural interfaces.

Defense Applications
Nanoscale sensing approaches have significant potential for the detection of for threat agents including biological, chemical, and radiological materials. Submissions in this topic area may also address sample formats and novel analytical schemes.

Environmental Applications
There is an increasing demand for sensors to assess and monitor environmental parameters that affect human health including pollutants and pathogens such as viruses and bacteria. Developments in sensor technology are critical for measuring air and water quality and for assessment during remediation efforts. Papers describing novel approaches for sensing in a variety of environmental formats are invited.

Novel approaches and instrumentation
Fundamental to all applications areas are core developments in materials and techniques for nanoscale sensing. Submissions are invited on novel materials, technologies and instrumentation.

Journal Submissions

Nanomedicine Journal

Nanomedicine: Nanotechnology, Biology and Medicine (Nanomedicine)

Nanomedicine: Nanotechnology, Biology and Medicine (Nanomedicine) is a newly established, international, peer-reviewed journal published quarterly. Nanomedicine publishes basic, clinical, and engineering research in the innovative field of nanomedicine. Article categories include basic nanomedicine, diagnostic nanomedicine, experimental nanomedicine, clinical nanomedicine, and engineering nanomedicine, pharmacological nanomedicine.

For consideration into the Nanomedicine: Nanotechnology, Biology and Medicine journal please select the “Submit to Nanomedicine: Nanotechnology, Biology and Medicine” button during the on-line submission procedure.

Experimental Nanoscience

Journal of Experimental Nanoscience

Selected Nanotech Proceedings papers will be reviewed and invited into a Special Issue of the Journal of Experimental Nanoscience. The journal provides a showcase for advances in the experimental sciences underlying nanotechnology and nanomaterials.

For consideration into this Special Issue of the Journal of Experimental Nanoscience, please select the “Submit to Journal of Experimental Nanoscience” button during the on-line submission procedure.

 

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Please contact: Denise Lee


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Medical & Biotech

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