Bionanobots for Drug-Delivery

R.B. Gonçalves

Keywords: drug delivery, molecular modeling, dendrimers, nanotecnology, tuberculosis


In this work we report a simulation of a bionanobots, for treatment of tuberculosis. Across molecular dynamics we simulate dendrimers of three generations with different pH conditions. We describe the specifics of the complexation and encapsulation of rifampicin inside dendrimer. We also developed an algorithm for coupling molecules inside dendrimers in optimal positions. These results were validated across experimental results of our group not showed here.