Nanoparticles for cardiovascular molecular imaging |
| Matthias Nahrendorf
Assistant Professor
Massachusetts General Hospital, Center for Systems Biology
|
My current research interests focus on imaging of molecular processes during
the healing phase after myocardial infarction. Imaging targets are innate
immune cells. Monocytes and macrophages are key players with a central role
in disease, including the development of heart failure. We use the entire
spectrum of modalities, including MRI, nuclear and optical imaging
techniques. Multimodal imaging, as well as hybrid approaches to fuse
molecular data with anatomical information are aspects of particular
interest. These technologies are embedded in a biologically driven research
program that aims at systematic understanding of inflammation at a basic
level while keeping a rigorous translational perspective. In addition, I
serve as the Director of the Mouse Imaging Program at the Center for Systems
Biology. In this function, I oversee the scientific and administrative
aspects of a broad molecular imaging facility that comprises all modalities,
lead and mentor a team of post doctoral researchers and technicians and
support collaborative imaging projects with outside researchers focusing on
cardiovascular disease and cancer.