Nanotech 2011

Designer Nanoparticles for Therapeutic Delivery (invited presentation)

S. Mitragotri
University of California, Santa Barbara, US

Keywords: nanomedicine, soft nanoparticles, flexibility, targeting

Abstract:

Polymeric nanoparticles have wide application in varied fields including drug delivery and medical imaging. Particle’s properties have significant impact on their therapeutic performance including circulation half-life, drug release rates and toxicity. Our research aims at developing quantitative guidelines describing the relationships between nanoparticle design and their performance as a drug delivery carrier. We particularly focus on engineering particle shape and flexibility, design parameters that have received little attention in the past.
 

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