Nanotech 2011

Concentration and characterization of influenza antigen bulks for potential novel vaccine delivery applications

A. Scampini, S. Gallorini, B.C. Baudner, G. Palladino, M. Singh, D.T. O’Hagan, S. Kommareddy
Novartis, US

Keywords: Influenza vaccine


As a part of reformulating influenza vaccines by novel delivery technologies it is essential to work with concentrated antigens. The purpose of this study was to concentrate seasonal influenza monobulks, to characterize the concentrated antigens in vitro, and to evaluate the concentrated antigens for in vivo immunogenicity.

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