Nanotech 2011

A Model for Enhanced Chemiluminescence Reactions in Microsystems

J. Berthier, P. Joly, F. Rivera, P. Caillat
CEA-LETI, FR

Keywords: chemiluminescence, active pixel sensor, diffusion, Michaelis Menten, Beer-Lambert

Abstract:

Detection of hybridized targets—like DNA strands—in microsystems for biotechnology is usually done by fluorescence. However, recent investigations have shown that chemiluminescence could be a more effective and sensitive tool for detection under the condition that dispersion of light due to diffusion is not too important. In this study, a model for an enhanced chemiluminescence reaction using luminols is proposed and the resulting light emission and absorption by a CMOS APS (active pixel sensor) is calculated.
 

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