Nanotech 2010

PEGylated Nanoceria: An Efficient Antioxidant in Glutathione depleted Mammalian cells

S. Singh, A. Karakoti, S. Seal, W. Self
University of Central Florida, US

Keywords: ceria, glutathione, free radicals

Abstract:

Here we have observed protection in mammalian cells (HaCat)by cerium oxide nanoparticles under deceased glutathione levels. Cell viability and intracellular reactive oxygen species level was monitored by LDH release and confocal microscopy respectively.
 
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