Nanotech 2010

Nanoemulsion Formation and characterization of Neutraceutical Components with the Sonication and Self-Assembly Methods

A.J. Choi, C.B. Park, C.G. Park, S.H. Han
Rural Development Administration, KR

Keywords: nanoemulsion, neutraceutical components, herbal crop, self-assembly, sonication


In this research, we investigated the optimum condition for the preparation of O/W nanoemulsion containing surfactants, neutraceutical ingredients extracted from Angelica gigas Nakai and oil phase in ternary phase diagrams of systems, and characterized the stability and formation of nanoemulsions. Various types of nanoemulsion including single-layer and double-layers nanoemulsions could be produced depending on the polyelectrolytes such as alginate and chitosan. O/W nanoemulsions of neuraceutical ingredients could be prepared by the ultra-sonication process and by self-assembly method with a particle size of 20-100nm and having a good stability during storage. The self-assembly method have an advantage with using low energy, but have a defect of using with many amounts of synthetic surfactants. Therefore the ultra-sonication method may be more powerful tool to prepare the nanoemulsion than the self-assembly method, it might be due to the formation capacity of nanoemulsion phase.
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