Nanotech 2010

Nuclear Uptake of Polymer-Lipid Nanoparticle in Multi Drug Resistant Breast Cancer Cells Via Caveolae Mediated Endocytosis and Macropinocytosis

P. Prasad, A. Shuhendler, M. Rauth, X.Y. Wu
University of Toronto, CA

Keywords: nanoparticle, endocytosis, multidrug resistant,

Abstract:

The uptake mechanism of polymer lipid nanoparticle was studied in multri drug resistant breast cancer cells. It was observed that caveolae and macropinocytosis mediated mechanisms played a role in the intracellular trafficking of the particle.
 
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