Nanotech 2010

From Micro to Nano Magnetic Spheres: Size-Controllable Synthesis, Multilayer Coatings, and Biomedical Applications

K.C.F. Leung, S. Xuan
The Chinese University of Hong Kong, HK

Keywords: nanoparticles, microparticles, magnetic, coating, MRI


Magnetic material has become a particular important research area and is attracting a great deal of attentions because of their potential technological applications, such as in ferrofluids, colored pigments, high-density magnetic recording media, chemical sensors, electrophotographic developers, biological assays and magnetic resonance imaging (MRI). In our group, size-controllable monodispersed ferrite nano to microspheres have been synthesized with a range of sizes from 20 nm to 300 nm. Some of these spheres have been coated efficiently with silica, carbon, gold, poly(aniline), dendrimers, etc. to yield well-defined core-shell structures. These magnetic microspheres were functionalized successfully with organic moieties such as crown ethers, acting as a tool for the preparation and magnetic separation of monofunctional gold nanoparticles. Moreover, ultrasmall magnetic nanospheres have been employed as both in vitro and in vivo MRI contrast agents.
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