Biosensing, Diagnostics & Imaging

Symposium Co-Chairs

Srinivas Iyer
Bioscience Division
Los Alamos National Laboratory

Manuel Perez
Assistant Professor of Chemistry and Nanoscience Technology
University of Central Florida

Confirmed Invited Speakers

	Functional nanocrystals as tunable platforms for imaging and sensing Hedi Mattoussi Professor, Department of Chemistry & Biochemistry, Florida State University
	Kirk D. Rector Materials Chemistry, Sensing and Imaging Team Leader Los Alamos National Laboratory

	Novel Gold Nanoparticles for Cancer Photoacoustic Imaging Zhen Cheng Assistant Professor, Radiology - Nuclear Medicine, Stanford University
	Jim Werner Technical Staff Member Center for Integrated Nanotechnologies, LANL

Symposium Sessions
	Tuesday June 19
10:30	Biosensing, Diagnostics and Imaging I
12:30	Networking Lunch - Expo
1:30	TechConnect IP Partnering: Biotech & Biosciences
2:00	Biosensing, Diagnostics and Imaging II
2:45	TechConnect IP Partnering: Medical, Pharma, Personal Care
4:00	Financing Emerging Technology Commercialization, Greenberg Traurig
4:30	Expo Reception and Poster Session I
	Biosensing, Diagnostics & Imaging
	Cancer Nanotechnology
	Wednesday June 20
8:30	Cancer Nanotech I
10:30	Cancer Nanotech II
12:30	Networking Lunch - Expo
1:00	NNI - Director's Networking Session, National Nanotechnology Coordination Office
1:30	Exhibit and Poster Session II
	Cancer Nanotechnology
3:30	Cancer Nanotech III
5:30	TechConnect Innovation Showcase Reception
6:00	CTSI Utility Technology Challenge Awarde and Reception
	Thursday June 21
10:00	National Nanotechnology Initiative Triennial Review
10:30	Biosensing, Diagnostics and Imaging III
12:30	Networking Lunch - Innovation Showcase
1:30	Biosensing, Diagnostics and Imaging IV
2:30	TechConnect Start-Up Partnering: Medical, Pharma, Personal Care
4:00	TechConnect Start-Up Partnering: Biotech, Biomaterials & Biosciences
4:00	TechConnect National Innovation Showcase, Reception & Poster Session III

Symposium Program
	Tuesday June 19
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10:30	Biosensing, Diagnostics and Imaging I	Great America J
	Session chair: Srinivas Iyer, Los Alamos National Laboratory & Manuel Perez, University of Florida, US
10:30	Functional nanocrystals as tunable platforms for imaging and sensing H. Mattousi, Florida State University, US
11:00	Time-Resolved Three Dimensional Molecular Tracking in Live Cells J. Werner, Los Alamos National Lab, US
11:30	Novel Gold Nanoparticles for Cancer Photoacoustic Imaging Z. Cheng, Stanford University, US
12:00	TBA K. Rector, Los Alamos National Lab, US
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12:30	Networking Lunch - Expo	Expo Hall AB
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1:30	TechConnect IP Partnering: Biotech & Biosciences	Room 212
	Session chair: Lynn Foster, BPT Pharma, US
1:30	New Compound Activates Broad Spectrum Lung Immunity N. Zelver, Montana State University Technology Transfer, US
1:40	Novel Agents to Enhance Tolerance to an Immunogen N. Zelver, Montana State University Technology Transfer, US
1:50	Glycine N-methyltransferase (GNMT) Animal model and use thereof Y.M. Chen, National Yang-Ming University, TW
2:00	Novel Single Dose Sterilant for Male and Female Companion and Feral Animals R. Kulkani, University of Kansas Center for Technology Commercialization, US
2:10	A Novel Protein Folding System R. Kulkani, University of Kansas Center for Technology Commercialization, US
2:20	Non-Viral Nanoparticle-Based Delivery System M. Malhotra, McGill University, CA
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2:00	Biosensing, Diagnostics and Imaging II	Great America J
	Session chair: Srinivas Iyer, Los Alamos National Laboratory & Manuel Perez, University of Florida, US
2:00	Gold Nanoparticles as a Surface to Immobilize Gadolinium-Hydroxypyridinone (HOPO) Complexes for Use a Magnetic Resonance Imaging (MRI) Contrast Agents P.J. Klemm, P.J. Straney, M.N. Keyser, J.E. Millstone, K.N. Raymond, UC Berkeley, US
2:20	A Metallofullerene Nanoparticle Platform for Imaging and Treatment of Glioblastoma Multiforme Tumors H.C. Dorn, J. Zhang, P. Fatouros, M.D. Shultz, J.D. Wilson, Virginia Polytechnic Institute and State University, US
2:40	Magneto-plasmonic Nanoplatforms for Enhanced Bioimaging and Photothermal Cancer Therapy A. Kopwitthaya, T.Y. Ohulchanskyy, M. Jeon, W-C. Law, Q. Xie, R.R. Chada, X. Xue, E.P. Furlani, C. Kim, P.N. Prasad, University at Buffalo (SUNY), US
3:00	Encapsulation of nanoparticles with multifunctional, cross-linkable diblock copolymers for biomedicine C. Schmidtke, J. Ostermann, H. Tran, E. Pöselt, H. Kloust, J. Niehaus, S. Becker, A. Kreuziger, K. Werner, A. Pietsch, H. Weller, University of Hamburg, DE
3:20	Fully integrated, multi-parametric flow cytometry chip using single layered three-dimensional (3D) hydrodynamic focusing A.A. Nawaz, X. Mao, T.J. Huang, Pennsylvania State University, US
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2:45	TechConnect IP Partnering: Medical, Pharma, Personal Care	Room 207
	Session chair: Belen Martinez-Lopez, CaramelTech, MX
2:45	NCap - NanoPorous Materials for Sustained Release W. Daniell, NanoScape AG, DE
2:55	Medical Nano-magnetic Drug Guidance A. Harel, NanoMed Targeting Systems Inc., US
3:05	Universal Optofluidic Chip for Ultra-Sensitive Raman Analysis of Liquid S. Mak, University of Toronto, CA
3:15	Next generation single dose vaccine adjuvants S. Niewiesk, The Ohio State University, US
3:25	Double Clad Fiber Coupler Allowing 3D Endoscopy T. Martinuzzo, Univalor, CA
3:35	Nanogold Assays for Direct Detection of Nucleic Acids of High Burden Infections H. Azzazy, The American University in Cairo, EG
3:45	A Liquid Crystal Polymer (LCP) Membrane MEMS Sensor for Flow Rate and Flow Direction Sensing, Medical and Environmental Applications L.M. Sim, Industry Liaison Office, National University of Singapore (NUS), SG
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4:00	Financing Emerging Technology Commercialization, Greenberg Traurig	Room 203
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4:30	Expo Reception and Poster Session I	Expo Hall AB
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	Biosensing, Diagnostics & Imaging
-	Novel and Rapid Assay for HIV Diagnosis and Drug Screening C. Esseghaier, C. Tlili, A. Ng, M. Zourob, Institut National de la Recherche Scientifique (INRS), CA
-	Continuous Sensing of blood by dark-field microscopy and surface-enhanced Raman Spectroscopy A.-I. Henry, B. Sharma, L.B. Sagle, R.P. Van Duyne, Northwestern university, US
-	Illuminating Epidermal Growth Factor Receptor Densities on Filopodia through Plasmon Coupling J. Wang, S.V. Boriskina, H. Wang, B.M. Reinhard, Boston University, US
-	Nanocomposites of Nanocrystalline Cellulose for Biosensors Applications V. Incani, C. Danumah, Y. Boluk, University of Alberta, CA
-	Cytotoxicity and genotoxicity evaluations for superparamagnetic iron oxide nanoparticles coated with various functional groups J. Lee, S. Hong, F. Sun, J. Lee, J. Kim, Pusan National University, KR
-	Gold nanoparticles as a tool to detect UTI and their cytotoxic effects in DU-145 cells P. Vedantam, J. Tzeng, A. Brown, R. Podia, K. Staley, A. Rao, Clemson University, US
-	Spectroscopic Ultra-Trace Detection of Nitroaromatic Gas Vapor on Rationally Designed Two-Dimensional Nanoparticle Cluster Arrays J. Wang, L. Yang, S. Boriskina, B. Yan, B.M. Reinhard, Boston University, US
-	A sensing properties study on miniature Au/SnO2 gas sensor for hydrogen sulfide detection B.W. Chang, S.J. Ding, R.L.C. Chen, HungKuang University, TW
-	CarouCELL – a novel compact submerged perfusion bioreactor for drug screening and tissue engineering M. Foss, D.Q.S. Le, Aarhus University, DK
-	An Integrated Microfluidic Real-Time PCR System for Pathogen Detection L. Zhu, L. Li, D. An, M. Wang, L. Zhang, Y.K. Wang, Z. Li, Y. Liu, G. Zhang, F. Lin, University of Manitoba, CA
-	DNA detection using Laser Transmission Spectroscopy F. Li, A.R. Mahon, M.A. Barnes, S. Egan, J. Feder, D.M. Lodge, C.-T. Hwang, R. Schafer, S.T. Ruggiero, C.E. Tanner, University of Notre Dame, US
-	Simultaneous Measurement of Nitric Oxide and Oxygen Dynamics during Myocardial Ischemia Reperfusion of Rat G.J. Lee, S.W. Kang, O.K. Kim, S.K. Kim, J.H. Shin, H.K. Park, Kyung Hee University, KR
-	The Effects of Temperature and Relative Humidity on the Stability of Paper-immobilized Antibodies J. Wang, B. Yiu, J. Obermeyer, C.D.M. Filipe, J.D. Brennan, R.H. Pelton, McMaster University, CA
-	Design of a noninvasive blood glucose Sensor J.M. Wang-Roveda, D. Nguyen, H.V. Nguyen, MIAO LLC, US
-	Opto-Fluidic Nanoparticle Detector D. Ou-Yang, X. Cheng, Lehigh University/ Foresight Science & Technology, US
-	Electromagnetic Particle Detector D. Ou-Yang, Lehigh University/ Foresight Science & Technology, US
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	Cancer Nanotechnology
-	Immunodiagnosis for cervical cancer using antibody-gold nanoparticle conjugate S. Tapaneeyakorn, C. Thepthai, N. Apiwat, T. Dharakul, National Science and Technology Development Agency, TH
-	Dual gold nanoparticles-enhanced sensitivity of colorimetric immunoassay for the visual detection of cervical cancer biomarker W. Maneeprakorn, N. Apiwat, S. Tapaneeyakorn, T. Dharakul, National Nanotechnology Center, National Science and Technology Development Agency, TH
-	Activation of Inflammasomes by Tumor Cell Death Mediated by Gold Nanoshells H.T. Nguyen, K.K. Tran, B. Sun, H. Shen, University of Washington, US
-	Targeted Cancer Therapy by Immunoconjugated Gold-Gold Sulfide Nanoparticles Using Protein-G as a Cofactor X.H. Sun, G.D. Zhang, D. Patel, A.M. Gobin, University of Louisville, US
-	Supermagnatic Iron Oxide Nanoparticles Toxicity to Mammalian Cells K. Vig, P. Tiwari, A. Parveen, V. Rangari, S.R. Singh, Alabama State University, US
	Wednesday June 20
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8:30	Cancer Nanotech I	Grand Ballroom A
	Session chair: Mansoor Amiji, Northeastern University, US
8:30	Top Down Nanotechnology for Cancer Diagnostics R. Bashir, University of Illinois, US
9:15	Nanoscience Strategies for the Design and Ultra Sensitive Readout of Dense Immunodiagnostic Platforms M. Porter, University of Utah, US
9:45	Fluid Biopsy in Solid Tumors, how HD-CTCs can provide real-time insights into cancer P. Kuhn, Scripps Physics Oncology Center; The Scripps Research Institute, US
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10:30	Cancer Nanotech II	Grand Ballroom A
	Session chair: Mansoor Amiji, Northeastern University, US
10:30	Nanomedicine for early detection of cancer and cancer therapy response monitoring D. Akin, Stanford University, US
11:00	Cell-Nanomaterial Interaction: Implications in Cell-Signaling and Targeted Therapy R. Kudgus, Mayo Clinic, US
11:30	Therapeutic gene silencing in vivo using RNA interference A. Sood, M.D. Anderson Cancer Center, US
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12:30	Networking Lunch - Expo	Exhibit Hall AB
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1:00	NNI - Director's Networking Session, National Nanotechnology Coordination Office	Exhibit Hall A
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1:30	Exhibit and Poster Session II	Exhibit Hall AB
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	Cancer Nanotechnology
-	Mn-Zn Ferrite and Photosensitizer Co-Loaded Cancer Theranostic Agent for Magnetic Resonance Imaging and Photodynamic Therapy S.-M. Lai, M.-D. Yang, M.-J. Tung, P.-S. Lai, National Chung Hsing University, TW
-	Copper complexes loaded on nanostructured TiO2 materials as citotoxic agents of cancer cells T. Lopez, E. Ortiz, P. Guevara, E. Gómez, Instituto Nacional de Neurologia y Neurocirugia, MX
-	Electrospun 5-fluorouracil loaded bovine serum albumin-polyvinylpyrrolidone nanofibers U.E. Illangakoon, N.P. Chatterton, G.R. Williams, T. Nazir, London Metropolitan University, UK
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3:30	Cancer Nanotech III	Grand Ballroom A
	Session chair: Mansoor Amiji, Northeastern University, US
3:30	Nano-Therapeutics for Blocking Multiple Targets: New Age for Combination Cancer Treatments J. Ljubimova, Cedars-Sinai Medical Center, US
4:00	Vascular and tumor imaging using targeted viral nanoparticles M. Manchester, University of California, San Diego, US
4:30	Systemic Responses to Targeted Nanoparticle Imaging and Theranostic Agents L. Yang, Emory University School of Medicine, US
5:00	Translational Cancer Nano-Medicine: Multimodal Strategies to Overcome Tumor Drug Resistance M. Amiji, Northeastern University, US
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5:30	TechConnect Innovation Showcase Reception	Expo Hall CD
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6:00	CTSI Utility Technology Challenge Awarde and Reception	Expo Theater 1
	Session chair: Patti Glaza, Arsenal Venture Partners, US
	Thursday June 21
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10:00	National Nanotechnology Initiative Triennial Review	Great America 1
	Session chair: Erik Svedberg, National Materials and Manufacturing, National Academies, US
10:00	NNI Town Hall Meeting TBD, National Nanotechnology Initiative, US
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10:30	Biosensing, Diagnostics and Imaging III	Room 204
	Session chair: Srinivas Iyer, Los Alamos National Laboratory & Manuel Perez, University of Florida, US
10:30	Rapid and sensitive detection of an intracellular pathogen in human peripheral leukocytes with hybridizing magnetic relaxation nanosensors M. Perez, University of Central Florida, US
11:00	PLGA-PEG multifunctional nanoparticles for simultaneous drug delivery and imaging by MRI and fluorescence microscopy A. Fornara, A. Chiavarino, J. Qin, M.S. Toprak, M. Muhammed, YKI - Institute for Surface Chemistry, SE
11:20	A Nanopore Biomimetic Device Quantitatively Detects Early Stage Cancer Cells; a Contour Map Multiple Variable Correlation Method Assesses the Heat of Cancer Cells Released E.T. Chen, Y. Shen J. Thornton, C. Ngatchou, S-H. Duh, P.T. Kissinger, Advanced Biomimetic Sensors, Inc., US
11:40	Novel three-dimensional porous film for single-cell microarray applications S. Ranjan, Z. Yong, National University of singapore, SG
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12:30	Networking Lunch - Innovation Showcase	Expo Hall CD
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1:30	Biosensing, Diagnostics and Imaging IV	Great America J
	Session chair: Srinivas Iyer, Los Alamos National Laboratory & Manuel Perez, University of Florida, US
1:30	Sample Preparation by On-Chip Dielectrophoretic Separation and Concentration of Viable, Non-Viable and Viable but Not Culturable (VBNC) Escherichia coli M. Packard, M. Shusteff, E. Alocilja, Michigan State University, US
1:50	Ultralow Detection of Bio-markers using Gold Nanoshells D. Patel, G. Zhang, X. Sun, A.M. Gobin, R.S. Keynton, University of Louisville, US
2:10	Breath acetone monitoring by portable Si:WO3 gas sensors M. Righettoni, A. Tricoli, S. Gass, A. Schmid, A. Amann, S.E. Pratsinis, ETH Zurich, CH
2:30	Disposable Coded Low Signal-Noise Ratio Single Cell Impedance Cytometry S. Emaminejad, M. Javanmard, R.W. Dutton, R.W. Davis, Stanford Genome Technology Center, US
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2:30	TechConnect Start-Up Partnering: Medical, Pharma, Personal Care	Expo Theater 2
	Session chair: Paul Prendergast, Merchant & Gould, US
2:30	IntuitiveMediCorp J.U. Kim, IntuitiveMediCorp, KR
2:40	Nano-Magnetic drug targeting A. Harel, NanoMed Targeting Systems Inc., US
2:50	Leukocyte coping capacity: stress-testing at your fingertips D. Sarphie, Oxford MediStress Ltd, US
3:00	Reagent-free nanobiomimetic electrochemical sensing platform E. Chen, Advanced Biomimetic Sensors, Inc., US
3:10	Magnetic nanotechnology for targeted cancer treatment T. Mitrelias, Cavendish NanoTherapeutics, UK
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4:00	TechConnect Start-Up Partnering: Biotech, Biomaterials & Biosciences	Expo Theater 2
	Session chair: Paul Prendergast, Merchant & Gould, US
4:00	Laser Transmission Spectroscopy C. Tanner, LightSprite, LLC, US
4:10	Novel Shape Memory foam devices for neurovascular and other vascular applications D. Maitland, Shape Memory Therapeutics, US
4:20	Biologue Continuous Glucose Monitoring System J. Willis, Ultradian Diagnostics LLC, US
4:30	Mobile Biosensors for Early Disease Detection V. Novotny, AltraSense Inc., US
4:40	Lux World Co., Ltd. S. Kang, Lux World Co., Ltd., KR
4:50	Disruptive wireless silicon platform for disposable wireless healthcare sensors S. Magar, HMicro, Inc., US
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4:00	TechConnect National Innovation Showcase, Reception & Poster Session III	Expo Hall CD

Special Symposium

This symposium will feature innovative applications-focused research and development in the following focus areas:

Nanoparticles in Imaging Technologies
Non-invasive imaging technologies for the diagnosis of disease typically involve the administration of contrast or signal enhancement agents that facilitate the visualization of organs or the state of a particular disease. Nanotechnology, particularly the development of nanoparticle-based agents, has had a tremendous impact in the design of targeted and specific nanoagents with the potential of homing on a particular area and interrogating for normal or disease processes. Submissions are invited on nanoparticle technologies for the visualization at the molecular or cellular level using magnetic resonance imaging (MRI), optical/fluorescent imaging, X-ray computed tomography (X-ray CT), ultrasound and positron emission tomography (PET), among others.

Clinical/Health Applications
One of the most significant impacts of the nanotechnology revolution is seen in the area of biomolecular analysis, which, as predicted by Feyman, has reached new levels of sensitivity, precision and resolution due to advances in the physical sciences. Submissions are invited on the development of biosensors for clinical and health applications. These may include point of care diagnostics, lab-on-a-chip integration, novel functionalization schemes, and the development of nano-neural interfaces.

Defense Applications
Nanoscale sensing approaches have significant potential for the detection of for threat agents including biological, chemical, and radiological materials. Submissions in this topic area may also address sample formats and novel analytical schemes.

Environmental Applications
There is an increasing demand for sensors to assess and monitor environmental parameters that affect human health including pollutants and pathogens such as viruses and bacteria. Developments in sensor technology are critical for measuring air and water quality and for assessment during remediation efforts. Papers describing novel approaches for sensing in a variety of environmental formats are invited.

Novel approaches and instrumentation
Fundamental to all applications areas are core developments in materials and techniques for nanoscale sensing. Submissions are invited on novel materials, technologies and instrumentation.

Journal Submissions

Nanomedicine: Nanotechnology, Biology and Medicine (Nanomedicine)

Nanomedicine: Nanotechnology, Biology and Medicine (Nanomedicine) is a newly established, international, peer-reviewed journal published quarterly. Nanomedicine publishes basic, clinical, and engineering research in the innovative field of nanomedicine. Article categories include basic nanomedicine, diagnostic nanomedicine, experimental nanomedicine, clinical nanomedicine, and engineering nanomedicine, pharmacological nanomedicine.

For consideration into the Nanomedicine: Nanotechnology, Biology and Medicine journal please select the “Submit to Nanomedicine: Nanotechnology, Biology and Medicine” button during the on-line submission procedure.

Journal of Experimental Nanoscience

Selected Nanotech Proceedings papers will be reviewed and invited into a Special Issue of the Journal of Experimental Nanoscience. The journal provides a showcase for advances in the experimental sciences underlying nanotechnology and nanomaterials.

For consideration into this Special Issue of the Journal of Experimental Nanoscience, please select the “Submit to Journal of Experimental Nanoscience” button during the on-line submission procedure.