Materials for Drug & Gene Delivery

Symposium Chair

Steven ZulloSteven Zullo
NIBIB/NIH

Confirmed Invited Speakers

Vinod LabhasetwarBiophysics of Cell Membrane Lipid-Nanoparticle Interactions: A New Paradigm in Drug Delivery and Targeting
Vinod Labhasetwar
Cancer NanoMedicine Lead, Cleveland Clinic Lerner Research Institute
Paul B FisherInnovative Approaches for Enhancing Cancer Gene Therapy
Paul B Fisher
Professor, Chair Dept. of Human Molecular Genetics, Virginia Commonwealth University
Stephen D MillerMARCO-Targeting Carboxylated PLG Nanoparticles Promote Tolerance Induction and Suppression of Inflammatory Monocytes
Stephen D Miller
Judy E. Gugenheim Professor of Microbiology-Immunology, Northwestern University Medical School
Marcelle MachlufTargeting Cancer With A Novel Mesenchymal Stem Cell-Derived Nano-Delivery Platform
Marcelle Machluf
Faculty, Technion - Israel Institute of Technology, Israel
Adah AlmutairiFine spatiotemporal control of thermolysis and lipolysis
Adah Almutairi
Co-Founder, eLux Medical, Inc.
Thomas AnchordoquyDrug Delivery to Tumors: the role of EPR
Thomas Anchordoquy
Professor, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado School of Pharmacy
Lee  JosephsonPEG-like Nanoprobes For Passive & Active Molecular Targeting
Lee Josephson
Associate Professor, Harvard Medical School
Alexander H  SteghHow functional genomics informs nano-drug design for precision cancer medicine
Alexander H Stegh
Assistant Professor, Robert H. Lurie Cancer Center, Northwestern University

Symposium Sessions

Tuesday June 17

10:30Materials for Drug & Gene Delivery I
3:00Materials for Drug & Gene Delivery II

Wednesday June 18

8:30Drug & Gene: Polymer NP based delivery systems
10:30Gold Nanotechnoloiges II
1:30Drug & Gene: Biologic targeting & delivery systems
Materials for Drug & Gene Delivery - Posters 4:00

Symposium Program

Tuesday June 17

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10:30Materials for Drug & Gene Delivery INational Harbor 2
Session chair: Steven Zullo, NIBIB/NIH, US (bio)
10:30Drug Delivery to Tumors: the role of EPR (invited presentation)
T. Anchordoquy, University of Colorado, Denver, US (bio)
10:55PEG-like Nanoprobes For Passive & Active Molecular Targeting (invited presentation)
L. Josephson, Harvard Medical School, US (bio)
11:20How functional genomics informs nano-drug design for precision cancer medicine (invited presentation)
A.H. Stegh, Robert H. Lurie Cancer Center, Northwestern University, US
11:45Enzyme-Directed Assembly of Nanoparticle Probes In Vivo
N.C. Gianneschi, L.M. Randolph, M.T. Proetto, A.M. Rush, M.-P. Chien, University of California, San Diego, US
12:05Treating brain tumors with targeted-micelles containing immunotherapeutics
A-M. Broome, S. Dixit, K. Miller, A. Moore, A-L. Bredlau, Medical University of South Carolina, US
12:25Non Toxic Water Soluble Nano Carbon Particles that can pass through the “Blood Brain Barrier” and have been conjugated with Taxol for sustained slow release
A. Allam, S. Sarkar, M. Ghosh, B. Pakhira, Cromoz Inc, US
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3:00Materials for Drug & Gene Delivery IINational Harbor 2
Session chair: Steven Zullo, NIBIB/NIH, US (bio)
3:00Targeting Cancer With A Novel Mesenchymal Stem Cell-Derived Nano-Delivery Platform (invited presentation)
M. Machluf, Technion - Israel Institute of Technology, Israel, US (bio)
3:25Selective biophysical interactions of surface modified nanoparticles with cancer cell lipids to improve tumor targeting and gene therapy (invited presentation)
V. Labhasetwar, Cleveland Clinic Lerner Research Institute, US (bio)
3:50β3 Integrin siRNA-Loaded Multifunctional Nanoparticle Therapy for Metastatic Breast Cancer
M. Gujrati, J.G. Parvani, W.P. Schiemann, Z.R. Lu, Case Western Reserve University, US
4:10Controlled Intracellular Release of Camptothecin by Glutathione-Driven Mechanism
P. Botella, C. Muniesa, V. Vicente, K. Fabregat, A. Cabrera, Instituto de Tecnología Química (UPV-CSIC), ES
4:30An innovative local strategy based on drug combined bone substitute
E. Verron, B. Bujoli, O. Gauthier, P. Janvier, J.M. Bouler, INSERM U791, FR
4:50Gel Microparticle System for Targeted Lung Delivery for the Treatment of Non-Small Cell Lung Cancer
N.M. Pinkerton, L. Shi, J. Wan, Z. Szekely, X. Zhang, P. Sinko, H.A. Stone, R.K. Prud’homme, Princeton University, US (bio)

Wednesday June 18

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8:30Drug & Gene: Polymer NP based delivery systemsPotomac 5
Session chair: Steven Zullo, NIBIB/NIH, US (bio)
8:30Fine spatiotemporal control of thermolysis and lipolysis (invited presentation)
A. Almutairi, eLux Medical, Inc., US (bio)
8:55Discovery of novel polymeric platinum nanoparticles for targeted drug delivery
M.T. Proetto, S.B. Howell, N.C. Gianneschi, University of California San Diego, US
9:15Engineering the quality and quantity of adaptive immunity against mucosally transmitted viral infections by using blend particle system
X. Zhan, H. Shen, University of Washington, US
9:35Biodegradable Polymer-Based Composite Particles for Targeted Drug Delivery Carriers with Magnetic Response
Y. Kitamoto, C. Oka, K. Ushimaru, T. Tsuge, N. Horiishi, Tokyo Institute of Technology, JP
9:55Ligand-modified nanoparticles as a multifunctional cancer
J.M. Silva, G. Vandermeulen, V.G. Oliveira, S. Pinto, E. Zupancic, L. Graca, V. Préat, H. Florindo, Faculty of Pharmacy University of Lisbon, PT
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10:30Gold Nanotechnoloiges IINational Harbor 2
Session chair: Trevor Keel, World Gold Council, UK (bio)
10:30Developing market opportunities for gold nanorod-based technologies (invited presentation)
B. Nikoobakht, NanoRodds LLC, US (bio)
10:55TNF Bound to PEGylated Gold Nanoparticles: a Platform for a Family of Cancer Nanomedicines (invited presentation)
L. Tamarkin, G.F. Paciotti, CytImmune Sciences Inc., US (bio)
11:20Spherical Nucleic Acids (SNAs) as Potent Gene Regulation and ImmunoModulatory Agents (invited presentation)
D. Giljohann, AuraSense, US (bio)
11:45Double-targeted theranostic gold nanoparticles for treatment of brain tumors
S. Dixit, Y. Zhu, A. Moore, M. Kenney, A-M. Broome, Medical University of South Carolina, US
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1:30Drug & Gene: Biologic targeting & delivery systemsNational Harbor 2
Session chair: Steven Zullo, NIBIB/NIH, US (bio)
1:30Innovative Approaches for Enhancing Cancer Gene Therapy (invited presentation)
P.B. Fisher, Virginia Commonwealth University, US (bio)
1:55MARCO-Targeting Carboxylated PLG Nanoparticles Promote Tolerance Induction and Suppression of Inflammatory Monocytes (invited presentation)
S. Miller, D. Getts, R. Terry, Z. Hunter, D. McCarthy, W. Yap, N. King, L. Shea, Northwestern University Medical School, US (bio)
2:20Centyrins: Targeted Delivery for Improved Therapeutics
D. Elias, K. O’Neil, J. Rojas, A. York, R.K. Prud’homme, Princeton University, US
2:40Selectively targeting endosomal toll-like receptor (TLR) signaling by blend nanoparticles and applications in cancer therapy
H. Shen, H.C. Chen, X. Zhan, M.J. Coyne, University of Washington, US
3:00Investigating Modified Oligonucleotides as Robust, Programmable Release Agents
V. Tohver Milam, N. Eze, Georgia Institute of Technology, US
3:20DNA-based Nanostructures for Therapeutic Delivery in Cancer
P. Charoenphol, H. Bermudez, University of Massachusetts Amherst, US
3:40Multimodal polymeric nanoparticles for Receptor Targeted delivery of Docetaxel in Prostate and Ovarian carcinoma
R. Singh, M. House, M. Norret, I. Larma, D. Ho, L.Y. Lim, N. Smith, S. South, T. St. Pierre, K. Swaminathan Iyer, The University Of Western Australia, AU
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Materials for Drug & Gene Delivery - Posters 4:00Potomac Registration Hall
-In Vitro Delivery of Docetaxel to Cancer Cells by Hybrid PLGA@Organosilica Nanoparticles with Redox-Sensitive Molecular Gates
P. Botella, M. Quesada, V. Vicente, A. Cabrera, K. Fabregat, Instituto de Tecnologia Química (UPV-CSIC), ES
-Study on the Composite with Sequential and Sustained Release of Multiple Growth Factors for Bone Repair
Y. Liao, T-Y Liu, Institute of Biomedical Engineering, National Yang-Ming University, TW
-Nanodelivery of Cerebrolysin as adjunct therapy with Functionalized magnetic iron oxide nanoparticles enhances neuroprotection
A. Sharma, D.F. Muresanu, Z.R. Tian, H. Moessler, H.S. Sharma, Uppsala University, SE
-On Designing Magnetic Vectors for DNA Vaccine Delivery
F.N. Al-Deen, C. Selomulya, C. Ma, S.D. Xiang, Y.Y. Kong, R. Coppel, M. Plebanski, Monash University, AU
-Nano-Power Implantable Autonomous Closed-Loop CMOS Nerve-Growth-Factor Delivery Microsystem for Neurological Disorders Personalized Therapy
M. Poustinchi, S Musallam, McGill University, Neural Prosthetics Laboratory, CA
-In vitro evaluation of a novel amphotericin B-loaded nanoemulsion: chemical stability and antifungal activity
F.B. Filippin-Monteiro, I.F. Kretzer, R.C. Maranhão, L.C. Souza, Federal University of Santa Catarina, BR
-Single cell dose-response studied by quantitative optical injection
G.V. Orsinger, J.D. Williams, M. Romanowski, University of Arizona, US
-Effect of Coating Materials on Cellular Uptake of Microparticles in HeLa Cells
N. Kato, A. Kojima, Meiji university, JP
-A novel interferon β1-A purification technology
L. Vaca, A. Sampieri, J. Zepeda, Universidad Nacional Autónoma de México, MX
-A Novel Filgrastim Production and Purification Technology
L. Vaca, A. Sampieri, J. Zepeda, Universidad Nacional Autónoma de México, MX
-Targeted delivery of temozolomide to pediatric brain tumors using micelle-based theranostic nanocarriers
K. Miller, S. Dixit, A-L. Bredlau, A-M. Broome, Medical University of South Carolina, US
-TiO2-Nanowired cerebrolysin attenuated hyperthermia induced ubiquitin overexpression and brain pathology
H.S. Sharma, D.F. Muresanu, R. Patnaik, H. Moessler, A. Sharma, Uppsala University, SE
-Applying Plasmon Resonant Coating to Commercial Liposomal Delivery Systems
S.S. Knights-Mitchell, University of Arizona, US
-Shell Thickness Control of Mesoporous Silica Hollow Capsules and Their Release Behavior
Y. Yamaguchi, N. Kato, Meiji university, JP
-Targeted Drug Delivery in Transplantation: Use of Immunosuppressant Nanoparticle Therapy
A-M. Broome, S.K. Dixit, N. Levey, C. Atkinson, S.N. Nadig, Medical University of South Carolina, US
-In vitro and In vivo Assessment of Liposomes and Chitosan Microparticles as Potential Carriers for Intravesical Delivery of Oxybutynin in the Treatment of Over Active Bladder
R. Felemban, G.D. Souza, H. Nguyen, C. Gridley, MCPHS University, US
-Synthesis and evaluation of T85-LPEI copolymers for pDNA delivery
M.X. Wang, Carolinas Medical Center, US
-Fabrication and characterization of core-shell microspheres composed of pectin and arabinoxylans as controlled release systems for insulin
J. Díaz-Baca, A.L. Martinez-Lopez, E. Carvajal-Millan, E. Pérez-López, H. González-Ríos, R. Balandrán-Quintana, A. Rascón-Chu, Centro de Investigacion en Alimentacion y Desarrollo A.C., MX
-Simulation and synthesis of a self-assembling and tumor-targeted drug delivery system
M. McTaggart, X. Li, C. Malardier-Jugroot, Royal Military College of Canada, CA
-Activation of antigen presenting cells and induction of mucosal antibodies by Chlamydia trachomatis outer membrane peptide encapsulated within PLA-PEG nanoparticles
S. Dixit, M. Taha, S.R. Singh, V.A. Dennis, Alabama State University, US
-Nano Drug delivery by Single-wall carbon nanotubes (SWCNTs) in the Central nervous system induces neurotoxicity. Potential neuroprotective effects of Cerebrolysin
H.S. Sharma, D.F. Muresanu, R. Patnaik, Z.R. Tian, H. Moessler, A. Sharma, Uppsala University, SE
-Antitumor efficacy of niclosamide loaded PEO:PEI fibers with tunable release profile
S. Uday Kumar, P. Gopinath, Indian Institute of Technology Roorkee, IN
-An Extrusion-Free and Scalable siRNA/Liposome Preparation for Efficient Encapsulation of siRNA by Simple Mixing
M.K. Lee, Korea Res. Inst. Biosci. Biotech. (KRIBB), KR
-A novel and facile approach for in situ synthesis of silver nanoparticles in nanofibers for antimicrobial wound dressing
P. Dubey, P. Gopinath, Indian Institute of Technology Roorkee, IN
-Effect of Magnetic Nanosphere Exposure on Neurite Extension and Branching
S. Sebastian, R.A. Veettil, T. Mcallister, S. Ghosh, D. Hynds, TEXAS WOMAN'S UNIVERSITY, US
-Endocytosis Mechanism of Surface Functionalized Nanoparticles in Neuronal Cells
R.A. Veettil, S. Sebastian, T. Mcallister, S. Ghosh, D. Hynds, TEXAS WOMAN'S UNIVERSITY, US
-Treating non-compressible hemorrhage with functionalized nanoparticles
D. Kudela, A. May-Masnou, C. Nguyen, J.R. Baylis, T. Chuong, C.F. Hebbard, A. Pallaoro, G.B. Braun, S.A. Smith, S. Hammond, L. Ferrigno, C.J. Kastrup, J.H. Morrissey, G.D. Stucky, UCSB, US

Special Symposium

Biocompatible materials with nano-scale structure hold great promise as controlled release reservoirs for delivery of both small-molecule drugs and various classes of biomacromolecules, such as peptides, proteins, plasmid DNA and synthetic oligodeoxynucleotides. Promising delivery systems include microcapsules, liposomes, macromolecular conjugates, nanoparticles, dendrimers, and biological nanostuctures such benign viruses and bacteriophages. This symposium will focus on success stories and reports of exciting new nanostructured materials and approaches for drug and gene delivery.

Topics & Application Areas

  • Targeting at molecular, cellular & higher levels
  • Antibody targeting
  • Modes of entry
  • Controlled release systems
  • Microcapsules
  • Liposomes
  • Polymer-based delivery systems
  • Protein/peptide delivery
  • Mitochondrial drug delivery
  • Novel delivery systems
  • Nanomedicine clinical trials: challenges & results
  • Other

Journal Submissions

Nanomedicine Journal

Nanomedicine: Nanotechnology, Biology and Medicine (Nanomedicine)

Nanomedicine NBM publishes articles on all issues related to nanomedicine, including the application of nanoscience and nanotechnology in biology and medicine.

Manuscripts must be directly or closely related to medicine (diagnosis, treatment, monitoring, prognosis and prevention of diseases) and supporting biology, especially understanding biologic mechanisms enabled by nanoscience, -engineering and -technology research, i.e.such as, research of man-made nanoscale objects, materials, and devices that improve medical procedures and outcome.

For consideration into the Nanomedicine: Nanotechnology, Biology and Medicine journal please select the “Submit to Nanomedicine: Nanotechnology, Biology and Medicine” button during the on-line submission procedure.

 

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