Materials for Drug & Gene Delivery

Materials for Drug & Gene Delivery

Symposium Chair

Steven ZulloSteven Zullo
NIBIB/NIH

Confirmed Invited Speakers

Adah AlmutairiThe Art of Falling Apart: On-demand Release from Polymeric Carriers
Adah Almutairi
Professor, Laboratory for Bioresponsive Materials, University of California, San Diego
Lily YangPromises and challenges in the translation of image-guided cancer therapy using theranostic nanoparticles
Lily Yang
Professor of Surgery, Winship Cancer Institute, Emory University School of Medicine
Fatih UckunOpportunities and Challenges for Personalized Cancer Therapy Using Biotargeted Nanomedicines
Fatih Uckun
Professor, USC Norris Comprehensive Cancer Center; CHLA Children’s Center for Cancer & Blood Diseases, Univ. of Southern California
Tom AnchordoquyOvercoming Delivery Obstacles with Cholesterol Nanodomains
Tom Anchordoquy
Professor, Department of Pharmaceutical Sciences, University of Colorado School of Pharmacy
Stephen MillerInduction of Tolerance for Therapy of Autoimmune Diseases Using Antigen-Linked Biodegradable PLG Nanoparticles – Mechanisms and
Stephen Miller
Judy E. Gugenheim Professor of Microbiology-Immunology, Northwestern University Medical School
Eva HarthNanosponge Delivery Systems: Superior targeted delivery through nanosolubilization, tailored release profiles and practical synthesis
Eva Harth
Associate Professor, Vanderbilt University
Robert K. Prud’hommeScaleable Polymeric Nanoparticle Formation for Multifunctional Drug Delivery and Imaging
Robert K. Prud’homme
Professor of Chemical and Biological Engineering, Director, Program in Engineering Biology, Princeton University
Laura ConfortiImmunotherapy with nanoparticles targeting ion channels: research and application challenges
Laura Conforti
Associate Professor, Pathobiology and Molecular Medicine, University of Cincinnati

Symposium Sessions

Tuesday May 14

11:00Materials for Drug & Gene Delivery I
Materials for Drug & Gene Delivery - Posters 1:30
3:30Materials for Drug & Gene Delivery II
4:30Innovation Spotlights: Pharma & Medical Devices

Wednesday May 15

10:30Materials for Drug & Gene Delivery III
11:00Innovation Spotlights: Pharma & Biotech
2:00Polymers for Drug and Gene Delivery
4:00Innovation Spotlights: Medical Devices
Materials for Drug & Gene Delivery - Posters 5:00

Symposium Program

Tuesday May 14

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11:00Materials for Drug & Gene Delivery IChesapeake 4-5
Session chair: Steven Zullo, NIBIB/NIH, US
11:00Materials for Drug & Gene Delivery: Veracity of Our Crystal Ball (invited presentation)
S. Zullo, NIBIB, US (bio)
11:10Nanosponge Delivery Systems: Superior targeted delivery through nanosolubilization, tailored release profiles and practical synthesis (invited presentation)
E. Harth, Vanderbilt University, US (bio)
11:35Promises and challenges in the translation of image-guided cancer therapy using theranostic nanoparticles (invited presentation)
L. Yang, W. Qian, M. Satpathy, L. Wang, G.Y. Lee, Z. Cao, R. Zielinski, J. Capala, S. Nie, Y.A. Wang, H. Mao, Emory University School of Medicine, US (bio)
12:00Scaleable Polymeric Nanoparticle Formation for Multifunctional Drug Delivery & Imaging (invited presentation)
R.K. Prud’homme, Princeton University, US
12:25Opportunities and Challenges for Personalized Cancer Therapy Using Biotargeted Nanomedicines (invited presentation)
F. Uckun, University of Southern California, US (bio)
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Materials for Drug & Gene Delivery - Posters 1:30Expo Hall A
-Cerium oxide nanoparticles alleviate experimental autoimmune encephalomyelitis in mice
J.S. Erlichman, M.L. Brackett, Cerion NRx LLC, US
-Targeted delivery of siRNAs against ion channels by lipid nanoparticles in T cell subsets
P. Hajdu, University of Cincinnati, US
-Novel Photo-thermal Controlled Drug-releasing Vectors for Cancer Detection and Treatment
M-H Tsai, D. Ling, M-J Shieh, National Taiwan University, TW
-Study on the polymeric nanosphere with imaging functionality
M-H Lin, T-Y Liu, Institute of Biomedical Engineering, National Yang-Ming University, Taipei, 112 Taiwan (ROC), TW
-Study of protoporphyrin IX-loaded silica hollow spheres for Photodynamic therapy
G-H Tseng, T-Y Liu, National Yang-Ming University of Taiwan, TW
-Nanovesicle‐Bioactive Conjugates Prepared by a One‐Step Scalable Method
N. Ventosa, I. Cabrera, E. Elizondo, O. Esteban, J.L. Corchero, M. Melgarejo, D. Pulido, A. Córdoba, E. Moreno, U. Unzueta, CSIC, ES
-Effect of cholesterol on the transfection efficiency of DOTAP-containing lipoplexes
D. Pozzi, F. Cardarelli, F. Salomone, C. Marchini, H. Amenitsch, G. Caracciolo, Sapienza University of Rome, IT
-Tailored, Linear Release with Modular Nanosponge Delivery Systems
E. Harth, D. Stevens, G. Li, Vanderbilt University, US
-Strategy to produce low molecular weight chitosan nanoparticles for gene/vaccine therapy with controllable polidispersity
C.C. Sipoli, N. Santana, L.G. de La Torre, State University of Campinas (UNICAMP), BR
-Approaches to surface-functionalised materials for biomedical applications
D.W. Pitt, A. Treharne, M.C. Grossel, University of Southampton, UK
-Reduction-sensitive hyaluronic acid nanoparticles for targeted intracellular deliery of doxorubicin
G. Saravanakumar, J.M. Shin, W. Um, J.H. Park, Sungkyunkwan University, KR
-Thermosensitive Vaginal Gel Containing PLGA-NTRI Conjugate Nanoparticles for HIV Prophylaxis
A. Rajca, Q. Li, A. Date, C. Destache, Creighton University School of Pharmacy & Health Professions, US
-Colloidal Structures of Micro-and Nano- Drug Particles in Polymeric Networks
P. Takhistov, P. Huynh, Rutgers, the State University of New Jersey, US
-Development of Drug Delivery System Using Bio based Calcium carbonate Nanoparticles
D. Render, V. Rangari, T. Samuel, J. Ramapuram, K. Pawar and S. Jeelani, Tuskegee University, US
-Endothelial cell derived exosome nanoparticle to deliver siRNA
A. Banizs, T. Huang, J.S. Lee, W. Shi and J. He, University of Virginia, US
-The potential applications of SOS-lux biosensors for rapid screening of mutagenic chemicals
H.A. Alhadrami, G.I. Paton, University of Dammam, KSA, & University of Aberdeen, UK, SA
-Microfluidic Impedance-Metric Biosensor for Monitoring Carbon Nanotube-Induced Epithelial Permeability
Z. Huang, N. Wu, Y. Rojanasakul, Y. Liu, West Virginia University, US
-A sensitive protein detection based on fluorescent dye-doped silica nanoparticles and lateral flow test strip
S. Bamrungsap,C. Apiwat, T. Dharakul and N. Wiriyachaiporn, NANOTEC Thailand, TH
-Key parameters to control the design of CycloRGD multimodal Imaging contrast agent
J. Bolley, O. Haddad, E. Guenin, Y. Lalatonne, L. Motte, Paris 13 University, FR
-Superparamagnetic Nanoparticles for Immuno Imaging of Brain Tumors by IRM
S. Richard, A. Herbet, Y. Lalatonne, S. Mériaux, F. Ducongé, J-P. Hugnot, E. Guénin, D. Boquet, L. Motte, Université Paris 13 - UFR SMBH, FR
-Discovery and characterization of the sensing modalities of novel diamond-graphene hetero-structures
M. Bockrath, I. Kierk, California Institute of Technology, US
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3:30Materials for Drug & Gene Delivery IIChesapeake 4-5
Session chair: Steven Zullo, NIBIB/NIH, US
3:30The Art of Falling Apart: On-demand Release from Polymeric Carriers (invited presentation)
C. de Gracia Lux, M.L. Viger, N. Fomina, J.E. Olejniczak, A. Almutairi, University of Californi, San Diego, US (bio)
3:50Overcoming Delivery Obstacles with Cholesterol Nanodomains (invited presentation)
T. Anchordoquy, University of Colorado Denver, US (bio)
4:10Induction of Tolerance for Therapy of Autoimmune Diseases Using Antigen-Linked Biodegradable PLG Nanoparticles – Mechanisms and Clinical Prospects
S. Miller, D. Getts, A. Martin, D. McCarthy, R. Terry, Z. Hunter, W. Yap, M. Getts, M. Pleiss, X. Luo, N. King, L. Shea, Northwestern University Medical School, US (bio)
4:30Deploying RNA and DNA using a functionalized carbon nanotube platform: implications for gene delivery
S. Alidori, K. Asqiriba, P. Londero, M. Bergkvist, M. Leona, D.A. Scheinberg, M.R. McDevitt, Memorial Sloan-Kettering Cancer Center, US
4:50Nanosystem for targeting Treg in vivo
M. Bottini, C. Sacchetti, N. Rapini, N. Rosato, A. Magrini, N. Bottini, Sanford Burnham Medical Research Institute, US
5:10Multifunctional squalenoyl nanocomposites for pancreatic cancer: diagnostic and therapeutic aspects
S. Valetti, B. Stella, S. Mura, D. Desmaële, F. Maione, E. Giraudo, L. Cattel, P. Couvreur, University of Paris, FR
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4:30Innovation Spotlights: Pharma & Medical DevicesPotomac 2
Session chair: Lynn Foster, BPT Pharma, US
4:30Language Analysis Tool Detects Cognitive Dysfunction for Early Alzheimer Diagnosis
A. Morrow, University of Minnesota, US
4:37Treating type 2 diabetes using menin inhibitors to regenerate insulin producing beta cells
F. Leu, Novapeutics LLC, US
4:44Integrated Continuous Manufacturing (ICM) of Pharmaceuticals
S. Mascia, CONTINUUS Pharmaceuticals, US
4:51Highly Sensitive Micron Scale Multiple Biomarker Biosensor
C. Yilmaz, Biolom, LLC, US
4:58Personal Health Expert
V. Shusterman, PinMed, US
5:05Flex Technology Inc
W. Krause, Flex Technology Inc, US
5:12Pharmaceutical technology of pharmaceutical composition and pharmacology treatment for enhancement of morphine analgesia and prevention of morphine tolerance
C. Laino, Biotechnology Institute, National University of La Rioja, AR
5:19Modular Biocompatible Materials for Medical Devices and Wound Healing Applications
S. Foster, Diazamed-CSU Ventures, US

Wednesday May 15

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10:30Materials for Drug & Gene Delivery IIIChesapeake 1-3
Session chair: Steven Zullo, NIBIB/NIH, US
10:30Immunotherapy with nanoparticles targeting ion channels: research and application challenges (invited presentation)
L. Conforti, University of Cincinnati, US (bio)
10:55Programming and switching the pharmacokinetics of nanoscale delivery vehicles in vivo
M.-P. Chien, N.C. Gianneschi, University of California, San Diego, US
11:15Magnetic Field-Induced Cyclizations of Amino-Esters and -Carbonates Bound to Iron Oxide Nanoparticles
R.J. Knipp, O. Uradu, M.H. Nantz, University of Louisville, US
11:35Gold-Coated Liposomes Encapsulating Signaling Molecules for Initiating Cellular Communication
G.V. Orsinger, M. Romanowski, University of Arizona, US
11:55Magnetically driven drug release from Fe3O4-phage network
C.B. Mao, University of Oklahoma, US
12:15NanoBandage for Controlled Release of Topical Therapeutics
M. Patchan, X. Calderon-Colon, J. Benkoski, M. Theodore, H. Le, B. Fuller, N. Boggs, A. Nelson, L. Garza, K. Sarkar, G. Brandacher, J. Patrone, The Johns Hopkins University Applied Physics Laboratory, US
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11:00Innovation Spotlights: Pharma & BiotechPotomac 3
Session chair: Belen Martinez-Lopez, CaramelTech, MX, Reviewers: Roche, Sanofi, Merck, Jennifer Gottwald, WARF, US
11:00Roche - Strategic Innovation Interests
M. Wetzel, Roche, US
11:15Sanofi - Strategic Innovation Interests
S. Natesan, Sanofi, US (bio)
11:30Merck - Strategic Innovation Interests
S. Xanthoudakis, Merck, US (bio)
12:00Targeted Drug Delivery System/Keystone Nano
D. Fecko, Penn State Materials Research Institute, US
12:07Novel SiO2-based antioxidant compound with significantly extended life-time and activity
G. Sotiriou, ETH Zurich – ETH transfer (the Technology Transfer Office), CH
12:14Diabetes Control Algorithms and Clinical Trial Software
S. Juncal, UCSB Office of Technology & Industry Alliances, US
12:21Biodegradable Polymer for Biomedical Applications
L. Besemann, University of Minnesota, US
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2:00Polymers for Drug and Gene DeliveryChesapeake 1-3
Session chair: YuanQiao Rao, Dow Chemical Company, US
2:00Non-ionic Dendronized Multiamphiphilic Polymers as Nanocarriers for Biomedical Applications
S. Gupta, B. Schade, S. Kumar, C. Böttcher, R. Haag, S.K. Sharma, University of Delhi, IN
2:20New biodegradable polymers based on previously unknown functional groups for drug and gene delivery
J. Yoo, T.A. Graf, D.J. Kuruvilla, S.R. D’Mello, A.K. Salem, N.B. Bowden, University of Iowa, US
2:40Reverse Thermoresponsive Polymers for Sustained Delivery of Therapeutic Agents
R. Mayadunne, A. Balachandra, T. Gunatillake, C. Lindall, CSIRO, AU
3:00Exploiting the “protein corona effect” for targeted drug and gene delivery
G. Caracciolo, D. Pozzi, A.L. Capriotti, C. Cavaliere, F. Cardarelli, F. Salomone, A. Laganà, Sapienza University of Rome, IT
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4:00Innovation Spotlights: Medical DevicesPotomac 1
Session chair: Allen Dines, University of Wisconsin-Madison, US
4:00Fiberoptic Microneedle Device for Convection-Enhanced Thermochemotherapy of Malignant Glioma
C. Rylander, Virginia Tech Intellectual Properties, Inc., US
4:07CANCELED - Operation system of laparoscope using pneumatically driven robotic holder
M. Yamamoto, Japan Technology Group Inc., JP
4:14A high throughput one-step assay for circulating tumor cell detection in whole blood sample
Y. Zu, The Methodist Hospital, US
4:21CereScope™ - A Portable All-in-One Neurological Monitoring System
R. Kern, Optima Neuroscience, Inc., US
4:28Medipacs Mini-Infuser™
M. Banister, Medipacs.com, US
4:35Flat Panel X-ray Sources
M. Eaton, Stellarray, US
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Materials for Drug & Gene Delivery - Posters 5:00Maryland
-Combinatorial Cationic Lipid-like Nanoparticles for Efficient Intracellular Cytotoxic Protein Delivery
Q.B. Xu, M. Wang, Tufts University, US
-Lipid nanoparticles for enhancing immune responses to protein antigens
T. Courant, H.L. Reynaud, A. Hoang, C. Villiers, F. Mittler, I. Texier, P.N. Marche, F.P. Navarro, CEA LETI MINATEC, FR
-Surface and Sefl-Associaciation Interaction of Proteins Characterized by QCM-D
A. Jaiswal, M. Poggi, Biolin Scientific, Inc., US
-Anchoring of self-assembled plasmid DNA/anti-DNA antibody /cationic lipid micelles on bisphosphonate-modified stent for cardiovascular gene delivery
G.L. Ma, Y. Wang, I. Fishbein, M. Yu, L.H. Zhang, I.S. Alferiev, J. Yang, C.X. Song, R.J. Levy, Chinese Academy of Medical Sciences and Peking Union Medical College, CN
-Fabrication of stable bio-compatible mesoporous silica and core-shell silica-magnetite nanoparticles for potential application in drug delivery
M.E. Sharifabad, T. Mercer, T. Sen, University of Central Lancashire, UK
-A New DNA-Based Carrier for Targeting and Intracellular Transport of Therapeutics
S. Muro, University of Maryland College Park, US
-Commercializing unique nanoparticle-imaging-delivery platform technology for enhanced cancer therapy
A. Fu, NVIGEN, Inc., US
-Cationic lipid nanoemulsions for RNAi screening
J. Bruniaux, E. Sulpice, F. Mittler, I. Texier, X. Gidrol, F.P. Navarro, CEA LETI MINATEC, FR
-Lysozyme – alginate nanocomplex: Effect of alginate composition
J.P. Fuenzalida, P.K. Nareddy, I. Moreno-Villoslada, B. Moerschbacher, M.J. Swamy, F.M.A. Goycoolea, Westfälische Wilhelms-Universität Münster, DE
-Near-Infrared Mediated Photothermal Ablation of Cancer Cells using Low Band Gap Polymer Nanoparticles
C.M. MacNeill, R.C. Coffin, D.L. Carroll, N.H. Levi-Polyachenko, Wake Forest University Health Sciences, US

Special Symposium

Biocompatible materials with nano-scale structure hold great promise as controlled release reservoirs for delivery of both small-molecule drugs and various classes of biomacromolecules, such as peptides, proteins, plasmid DNA and synthetic oligodeoxynucleotides. Promising delivery systems include microcapsules, liposomes, macromolecular conjugates, nanoparticles, dendrimers, and biological nanostuctures such benign viruses and bacteriophages. This symposium will focus on success stories and reports of exciting new nanostructured materials and approaches for drug and gene delivery.

Topics & Application Areas

  • Targeting at molecular, cellular & higher levels
  • Antibody targeting
  • Modes of entry
  • Controlled release systems
  • Microcapsules
  • Liposomes
  • Polymer-based delivery systems
  • Protein/peptide delivery
  • Pharmacodynamics
  • Novel delivery systems
  • Nanomedicine clinical trials: challenges & results
  • Other

Technical Abstract Submission

Please first review the information for authors as well as the abstract preparation guidelines.

 

Journal Submissions

Nanomedicine Journal

Nanomedicine: Nanotechnology, Biology and Medicine (Nanomedicine)

Nanomedicine NBM publishes articles on all issues related to nanomedicine, including the application of nanoscience and nanotechnology in biology and medicine.

Manuscripts must be directly or closely related to medicine (diagnosis, treatment, monitoring, prognosis and prevention of diseases) and supporting biology, especially understanding biologic mechanisms enabled by nanoscience, -engineering and -technology research, i.e.such as, research of man-made nanoscale objects, materials, and devices that improve medical procedures and outcome.

For consideration into the Nanomedicine: Nanotechnology, Biology and Medicine journal please select the “Submit to Nanomedicine: Nanotechnology, Biology and Medicine” button during the on-line submission procedure.

Nanoparticle Research

Journal of Nanoparticle Research

Selected Nanotech Proceedings papers will be reviewed and invited into a Special Issue of Journal of Nanoparticle Research. The journal disseminates knowledge of the physical, chemical and biological phenomena and processes in nanoscale structures.

For consideration into this Special Issue of Journal of Nanoparticle Research, please select the “Submit to Journal of Nanoparticle Research” button during the on-line submission procedure.

 

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