Targeting aberrant cancer kinome using rationally designed nano-polypharmaceutics

Manzoor Koyakutty

Manzoor Koyakutty

Professor & Group Leader- Cancer Nanomedicine Program

Amrita Institute of Medical Science, Cochin

India

Dr. Manzoor K is a Professor at ACNS specializing in the area of cancer nanomedicine, nanotoxicology and molecular finger-printing of cancer bio-markers. Dr. Manzoor K joined ACNS in June 2007. Prior to his current position, he served as Staff-Scientist at Defence Research and Development Organization (DRDO), Ministry of Defence, Govt. of India for about 10 years where he had extensive research experience in the design and development of functional nanosystems for defence applications. The Govt. of India has shown appreciation for his valuable contributions to the area of nanotechnology by conferring prestigious awards such as DRDO Technology Developer of the Year 2006, National Science Day Award-2005, DRDO Young Scientist of the Year 2004, and Best Laboratory Scientist of the Year 2003.

Currently, his team at ACNS focus on: targeted multifunctional nanomedicines for the diagnostic and therapy of drug resistant cancer and cancer stem cells using bio-friendly luminescent quantumdots, magnetic nanocrystals, nano-biomaterials showing x-ray, MR and near-infrared contrast, nanoscintillator quantumdots based x-ray dynamic therapy, plasmonic nanocrystals based RF hyperthermia, nano-siRNA conjugates based genes silencing and Raman spectroscopic finger printing of Onco-genes.

In 2008, Dr Manzoor K received the prestigious Marie-Curie IIF Award from European Commission to work with Erasmus Medical University, the Netherlands, for developing `Peptide targeted nanophotomedicines for molecular imaging guided laser therapy of cancer\\\\\\\' (Patent pending). He has written about 34 international publications and [05 patents (02 issued and 03 submitted).] He is a member of the European Society of Nanomedicine, the European Foundation of Clinical Nanomedicine and the American Association of Nanomedicine.

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