Investigation of the Concentration Polarization effect on Nanoparticles using radial micro-nanofluidic devices

K. Aïzel, Y. Fouillet, C. Pudda, C. Chabrol, I. Texier-Nogues
CEA LETI, FR

Keywords: nanochannel, nanoparticles, concentration polarization, nanojunction

Summary:

We perform ICP using radial silicon nanojunction geometries fabricated by single standard silicon microfabrication for proof of concept concentration operation over 50nm polystyrene nanobeads.We call the devices “Ring like devices” because of the circular shape of the nanojunction. The ion-selective nanojunction exhibits 4 radial nanochannels. Unlike previous concentration polarization based schemes; using the Ring like devices, our concentration process relies partly on the concentration zone that occurs at the cathodic side of the nanojunction in the circular micro chamber at the periphery of the circular nanochannel. Ion concentration zone allow for continious concentration of nanobeads up to ~1000 times the initial concentration over 1 hour. The concentration process is very stale and does not require any backflow for concentration operation. The strong and stable concentration effect of fluorescent nanoparticles is of special importance when it comes to consider the early detection of biological species such as viruses for instance.